{
  "id": 7860,
  "label": "ocular sebaceous carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006327",
  "properties": {
    "xrefs": [
      "EFO:1000405",
      "MEDGEN:317974",
      "NCIT:C43340",
      "UMLS:C1709308"
    ],
    "synonyms": [
      "eye sebaceous carcinoma",
      "ocular sebaceous carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "Ocular sebaceous carcinoma is a rare condition and accounts for 1% to 5.5% of eyelid malignancies and is the third most common eyelid malignancy after basal cell and squamous cell carcinoma. It usually affects elderly women, has a high rate of local recurrence, and a tendency to regional and distant metastases."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4546,
      "label": "eye carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4185,
        4353
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:295",
          "MEDGEN:208855",
          "NCIT:C6079",
          "UMLS:C0848866"
        ],
        "synonyms": [
          "carcinoma of eye",
          "carcinoma of eyeball of camera-type eye",
          "carcinoma of the eye",
          "eye carcinoma",
          "eyeball of camera-type eye carcinoma",
          "ocular carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the eye"
      },
      "child_count": 18,
      "reference_id": "MONDO:0002466"
    },
    {
      "id": 8388,
      "label": "sebaceous adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        8398,
        22966
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4839",
          "DOID:4840",
          "EFO:1001171",
          "ICDO:8410/3",
          "MEDGEN:64632",
          "MESH:D018266",
          "NCIT:C40310",
          "ONCOTREE:SEBA",
          "SCTID:307599002",
          "UMLS:C0206684"
        ],
        "synonyms": [
          "adenocarcinoma, sebaceous, malignant",
          "carcinoma of sebaceous gland",
          "carcinoma of the sebaceous gland",
          "sebaceous cancer",
          "sebaceous carcinoma",
          "sebaceous gland adenocarcinoma",
          "sebaceous gland carcinoma",
          "malignant sebaceous tumor",
          "malignant sebaceous tumour",
          "Seba"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An adenocarcinoma with sebaceous differentiation. It presents as a painless mass and it may be multifocal. It grows in the ocular adnexae and in the skin of head and neck, trunk, genitals, and extremities. It is characterized by the presence of malignant cells with multivesicular and clear cytoplasm. It may recur and metastasize."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006962"
    }
  ],
  "children": [
    {
      "id": 20681,
      "label": "eyelid sebaceous gland carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5740,
        7860
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025340",
          "MEDGEN:1612781",
          "NCIT:C134831",
          "Orphanet:658590",
          "UMLS:C4525405"
        ],
        "synonyms": [
          "carcinoma of sebaceous gland of eyelid",
          "eyelid SGC",
          "eyelid sebaceous gland carcinoma",
          "sebaceous gland carcinoma of the eyelid",
          "sebaceous gland of eyelid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A sebaceous gland carcinoma affecting the eyelid. It arises from the meibomian glands, glands of Zeis, or glands associated with the caruncle. It usually affects elderly women and is characterized by high rate of local recurrence, regional, and distant metastases."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021588"
    }
  ],
  "roots": [
    {
      "id": 4546,
      "label": "eye carcinoma"
    },
    {
      "id": 8388,
      "label": "sebaceous adenocarcinoma"
    }
  ]
}