{
  "id": 7864,
  "label": "ovarian endometrioid adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006335",
  "properties": {
    "xrefs": [
      "DOID:5828",
      "EFO:1000416",
      "GARD:0021893",
      "MEDGEN:91087",
      "NCIT:C7979",
      "ONCOTREE:EOV",
      "Orphanet:454723",
      "SCTID:254852002",
      "UMLS:C0346163"
    ],
    "synonyms": [
      "endometrioid adenocarcinoma of ovary",
      "endometrioid adenocarcinoma of the ovary",
      "endometrioid cancer of ovary",
      "endometrioid cancer of the ovary",
      "endometrioid carcinoma of ovary",
      "endometrioid carcinoma of the ovary",
      "endometrioid ovary carcinoma",
      "endometrium adenocarcinoma of ovary",
      "ovarian endometrioid adenocarcinoma",
      "ovarian endometrioid cancer",
      "ovarian endometrioid carcinoma",
      "ovary endometrium adenocarcinoma",
      "endometrioid ovarian cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "An endometrioid adenocarcinoma arising from the ovary. It comprises 10% to 25% of all primary ovarian carcinomas. Grossly, endometrioid carcinoma may present as a cystic or solid mass. Microscopically, the tumor greatly resembles the appearance of the ordinary type of endometrial adenocarcinoma. As a group, endometrioid carcinoma has a prognosis twice as good as that of serous or mucinous carcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4787,
      "label": "ovarian adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6712,
        6864
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3713",
          "EFO:0006460",
          "GARD:0020466",
          "MEDGEN:181757",
          "MedDRA:10051938",
          "NCIT:C7700",
          "Orphanet:213504",
          "UMLS:C0948216"
        ],
        "synonyms": [
          "adenocarcinoma of ovary",
          "adenocarcinoma of the ovary",
          "ovarian adenocarcinoma",
          "ovary adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An adenocarcinoma that arises from the ovary. It is the most common type of ovarian carcinoma. It includes the serous adenocarcinoma, mucinous adenocarcinoma, clear cell adenocarcinoma, and endometrioid adenocarcinoma."
      },
      "child_count": 14,
      "reference_id": "MONDO:0002752"
    },
    {
      "id": 5685,
      "label": "ovarian endometrial cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4560,
        18447
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6212",
          "GARD:0023680",
          "MEDGEN:276545",
          "NCIT:C40051",
          "UMLS:C1518231"
        ],
        "synonyms": [
          "endometrioid tumor of ovary",
          "endometrioid tumour of ovary",
          "malignant ovarian endometrioid tumor",
          "malignant ovarian endometrioid tumour",
          "ovary endometrioid tumor",
          "ovary endometrioid tumour",
          "ovary female reproductive endometrioid cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign, borderline, or malignant epithelial tumor of the ovary characterized by the presence of glands and/or cysts lined by neoplastic cells that resemble endometrial cells."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003812"
    },
    {
      "id": 6760,
      "label": "endometrioid adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3637,
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000466",
          "ICDO:8380/3",
          "MEDGEN:293976",
          "NCIT:C3769",
          "UMLS:C1569637"
        ],
        "synonyms": [
          "endometrioid adenocarcinoma",
          "endometrioid carcinoma",
          "endometrioid carcinoma of female reproductive system",
          "endometrioid carcinoma of the female reproductive system",
          "female reproductive endometrioid carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An adenocarcinoma characterized by the presence of malignant glandular epithelial cells resembling endometrial cells. It can arise from the uterine body, ovary, fallopian tube, cervix, vagina, and uterine ligament."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005026"
    },
    {
      "id": 7120,
      "label": "endometrium adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4530,
        6712
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2870",
          "EFO:0005232",
          "MEDGEN:218862",
          "NCIT:C7359",
          "UMLS:C1153706"
        ],
        "synonyms": [
          "endometrioid carcinoma of endometrium",
          "adenocarcinoma of endometrium",
          "adenocarcinoma of the endometrium",
          "adenocarcinoma, endometrial, malignant",
          "endometrial adenocarcinoma",
          "endometrioid adenoma or carcinoma NOS (morphologic abnormality)",
          "endometrioid adenomas and carcinomas (morphologic abnormality)",
          "endometrium adenocarcinoma",
          "endometrial endometrioid adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An adenocarcinoma arising from the uterine body cavity. This is the most frequent malignant tumor affecting the uterine body, and is linked to estrogen therapy. Most patients present with uterine bleeding and are over age 40 at the time of diagnosis. The prognosis depends on the stage of the tumor, the depth of the uterine wall invasion, and the histologic subtype. Endometrioid adenocarcinoma is the most frequently seen morphologic variant of endometrial adenocarcinoma."
      },
      "child_count": 18,
      "reference_id": "MONDO:0005461"
    }
  ],
  "children": [
    {
      "id": 7865,
      "label": "ovarian endometrioid adenocarcinoma with squamous differentiation",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7864
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000417",
          "GARD:0024372",
          "MEDGEN:389178",
          "NCIT:C40061",
          "UMLS:C2212017"
        ],
        "synonyms": [
          "ovarian adenoacanthoma",
          "ovarian adenosquamous carcinoma",
          "ovarian endometrioid adenocarcinoma with squamous differentiation"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An endometrioid adenocarcinoma that arises from the ovary and exhibits squamous differentiation. The squamous cell component often has a cytologically benign appearance."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006336"
    }
  ],
  "roots": [
    {
      "id": 4787,
      "label": "ovarian adenocarcinoma"
    },
    {
      "id": 5685,
      "label": "ovarian endometrial cancer"
    },
    {
      "id": 6760,
      "label": "endometrioid adenocarcinoma"
    },
    {
      "id": 7120,
      "label": "endometrium adenocarcinoma"
    }
  ]
}