{
  "id": 7876,
  "label": "papillary transitional cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006350",
  "properties": {
    "xrefs": [
      "DOID:4012",
      "EFO:1000450",
      "GARD:0024378",
      "ICDO:8130/3",
      "MEDGEN:137736",
      "NCIT:C4122",
      "UMLS:C0334274"
    ],
    "synonyms": [
      "papillary transitional carcinoma",
      "papillary transitional cell carcinoma (morphologic abnormality)"
    ],
    "definition": "A non-invasive or invasive transitional cell carcinoma characterized by a papillary growth pattern. It may occur in the bladder or the renal pelvis."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7972,
      "label": "transitional cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2671",
          "EFO:1000601",
          "GARD:0007794",
          "ICDO:8120/3",
          "MEDGEN:2875",
          "MESH:D002295",
          "NCIT:C2930",
          "UMLS:C0007138"
        ],
        "synonyms": [
          "transitional cell neoplasm",
          "transitional cell tumor",
          "transitional cell tumour",
          "carcinoma of transitional epithelial cell",
          "carcinoma of urothelial cell",
          "carcinoma, urothelial, malignant",
          "transitional carcinoma",
          "transitional cell carcinoma",
          "transitional epithelial cell carcinoma",
          "urothelial cell carcinoma"
        ],
        "definition": "A malignant neoplasm arising from the transitional epithelium, usually affecting the urinary bladder, ureter, or renal pelvis. It may or may not have a papillary configuration. It is graded 1 to 3 or 4 according to the degree of cellular differentiation and architectural patterns. Grade 1 transitional cell carcinoma is histologically benign but it may recur. Transitional cell carcinomas may also affect the upper respiratory tract and the ovaries."
      },
      "child_count": 9,
      "reference_id": "MONDO:0006474"
    },
    {
      "id": 8000,
      "label": "papillary carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        20336
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3113",
          "EFO:1000646",
          "ICDO:8050/3",
          "MEDGEN:40105",
          "MESH:D002291",
          "NCIT:C2927",
          "UMLS:C0007133"
        ],
        "synonyms": [
          "papillary carcinoma",
          "papillary carcinoma (morphologic abnormality)",
          "papillary carcinoma NOS (morphologic abnormality)"
        ],
        "definition": "A malignant epithelial neoplasm characterized by a papillary growth pattern. A papillary carcinoma may be composed of glandular cells (papillary adenocarcinoma), squamous cells (papillary squamous cell carcinoma), or transitional cells (papillary transitional cell carcinoma). Bladder carcinoma is a representative example of papillary transitional cell carcinoma."
      },
      "child_count": 10,
      "reference_id": "MONDO:0006509"
    }
  ],
  "children": [
    {
      "id": 5597,
      "label": "renal pelvis papillary urothelial carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5598,
        6936,
        7876
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5973",
          "GARD:0023630",
          "MEDGEN:237178",
          "NCIT:C6148",
          "UMLS:C1377909"
        ],
        "synonyms": [
          "kidney pelvis papillary carcinoma",
          "papillary carcinoma of kidney pelvis",
          "papillary carcinoma of renal pelvis",
          "papillary carcinoma of the kidney pelvis",
          "papillary carcinoma of the renal pelvis",
          "renal pelvis papillary carcinoma",
          "renal pelvis papillary urothelial carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A papillary transitional cell carcinoma that arises from the renal pelvis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003716"
    },
    {
      "id": 5897,
      "label": "bladder papillary urothelial carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5368,
        7252,
        7876
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6975",
          "GARD:0023797",
          "MEDGEN:309552",
          "NCIT:C7383",
          "UMLS:C1518882"
        ],
        "synonyms": [
          "bladder papillary urothelial carcinoma",
          "urinary bladder papillary transitional cell carcinoma",
          "urothelial papillary carcinoma of the bladder",
          "bladder urothelial papillary carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An invasive or non-invasive papillary transitional cell carcinoma of the urinary bladder. It is classified as low - or high-grade. -- 2003"
      },
      "child_count": 0,
      "reference_id": "MONDO:0004056"
    }
  ],
  "roots": [
    {
      "id": 7972,
      "label": "transitional cell carcinoma"
    },
    {
      "id": 8000,
      "label": "papillary carcinoma"
    }
  ]
}