{
  "id": 7901,
  "label": "pleural sarcomatoid mesothelioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006380",
  "properties": {
    "xrefs": [
      "EFO:1000486",
      "GARD:0024388",
      "MEDGEN:354059",
      "NCIT:C45663",
      "UMLS:C1709578"
    ],
    "synonyms": [
      "pleura sarcomatoid mesothelioma",
      "pleural sarcomatoid mesothelioma",
      "sarcomatoid mesothelioma of pleura"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "Malignant mesothelioma that arises from the pleura and is characterized by the presence of spindle-shaped cells forming fascicles, or that are distributed haphazardly resembling a sarcoma."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6838,
      "label": "malignant pleural mesothelioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5249,
        7834,
        7835
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7474",
          "EFO:0000770",
          "GARD:0024150",
          "MEDGEN:208810",
          "NCIT:C7376",
          "SCTID:254645002",
          "UMLS:C0812413"
        ],
        "synonyms": [
          "pleura mesothelioma",
          "malignant mesothelioma of pleura",
          "malignant mesothelioma of the pleura",
          "malignant pleural mesothelioma",
          "pleural diffuse malignant mesothelioma",
          "pleural malignant mesothelioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A malignant neoplasm that arises from mesothelial cells in the pleura and shows a diffuse growth pattern. It arises on the parietal and sometimes visceral pleura as multiple small nodules that later become confluent and invade the chest wall adipose tissue and muscle. Asbestos exposure is the main cause for the development of pleural malignant mesothelioma. It usually affects patients over sixty years of age. The latency period is long. Patients usually present with pleural effusion, dyspnea and chest wall pain. Additional signs and symptoms include chills, sweating, weight loss, and weakness. Morphologic variants include epithelioid, desmoplastic, sarcomatoid, and biphasic mesothelioma. The clinical course is usually aggressive."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005112"
    },
    {
      "id": 7926,
      "label": "sarcomatoid mesothelioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7834
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4488",
          "EFO:1000521",
          "GARD:0024401",
          "MEDGEN:137774",
          "NCIT:C45655",
          "UMLS:C0334513"
        ],
        "synonyms": [
          "malignant fibrous mesothelioma (morphologic abnormality)",
          "sarcomatoid mesothelioma",
          "sarcomatoid mesothelioma (morphologic abnormality)"
        ],
        "definition": "A diffuse malignant mesothelioma arising from the pleura and less often the peritoneum. It is characterized by the presence of spindle cells. Anaplastic morphologic features and multinucleated malignant cells may also be seen."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006407"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6838,
      "label": "malignant pleural mesothelioma"
    },
    {
      "id": 7926,
      "label": "sarcomatoid mesothelioma"
    }
  ]
}