{
  "id": 7903,
  "label": "poorly differentiated thyroid gland carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006382",
  "properties": {
    "xrefs": [
      "DOID:3972",
      "EFO:1000489",
      "ICDO:8337/3",
      "MEDGEN:266094",
      "NCIT:C6040",
      "ONCOTREE:THPD",
      "UMLS:C1266050",
      "icd11.foundation:1227619262"
    ],
    "synonyms": [
      "insular carcinoma",
      "poorly differentiated carcinoma of the thyroid gland",
      "poorly differentiated carcinoma of thyroid gland",
      "poorly differentiated thyroid carcinoma",
      "poorly differentiated thyroid gland cancer",
      "poorly differentiated thyroid gland carcinoma",
      "thyroid gland poorly differentiated carcinoma",
      "poorly differentiated thyroid cancer"
    ],
    "definition": "An adenocarcinoma arising from the thyroid gland showing only limited evidence of follicular cell differentiation. Microscopically, the adenocarcinoma cells are arranged in insular, solid, and trabecular patterns. There is associated necrosis, and vascular invasion. The prognosis depends on the tumor stage, complete or partial surgical removal of the tumor, and the degree of response to radioactive iodine therapy (adapted from WHO Tumors of Endocrine Organs, IARC Press, Lyon 2004)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6712,
      "label": "adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        21312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-0386",
          "DOID:299",
          "EFO:0000228",
          "ICDO:8140/3",
          "MEDGEN:122",
          "MESH:D000230",
          "NCIT:C2852",
          "ONCOTREE:ADNOS",
          "SCTID:443961001",
          "UMLS:C0001418"
        ],
        "synonyms": [
          "adenocarcinoma",
          "adenocarcinoma NOS (morphologic abnormality)",
          "adenocarcinoma, malignant",
          "adenocarcinoma, no subtype (morphologic abnormality)",
          "adenocarcinomas",
          "ADNOS"
        ],
        "definition": "A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma."
      },
      "child_count": 128,
      "reference_id": "MONDO:0004970"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6712,
      "label": "adenocarcinoma"
    }
  ]
}