{
  "id": 7921,
  "label": "salivary gland basal cell adenocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006402",
  "properties": {
    "xrefs": [
      "EFO:1000515",
      "GARD:0024399",
      "ICDO:8147/3",
      "MEDGEN:412203",
      "NCIT:C3678",
      "UMLS:C2243086"
    ],
    "synonyms": [
      "basal cell adenocarcinoma",
      "basal cell adenocarcinoma of salivary gland",
      "basal cell adenocarcinoma of the salivary gland",
      "saliva-secreting gland skin basal cell carcinoma",
      "salivary gland basal cell adenocarcinoma",
      "skin basal cell carcinoma of saliva-secreting gland"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      }
    ],
    "definition": "A rare adenocarcinoma of the major and minor salivary glands, originating from basaloid, myoepithelial and ductal cells. While morphologically resembling basal cell carcinomas, it is a distinct entity. The tumor is not encapsulated, may invade locally, and less frequently may metastasize. It usually occurs in older patients."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2972,
      "label": "salivary gland carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6453,
        23483
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050904",
          "GARD:0027535",
          "MEDGEN:215302",
          "NANDO:2200076",
          "NCIT:C9272",
          "ONCOTREE:SACA",
          "UMLS:C0948750"
        ],
        "synonyms": [
          "salivary gland cancer",
          "carcinoma of saliva-secreting gland",
          "carcinoma of salivary gland",
          "carcinoma of the salivary gland",
          "saliva-secreting gland carcinoma",
          "salivary gland carcinoma",
          "salivary carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A carcinoma that arises from the major or minor salivary glands. Representative examples include carcinoma ex pleomorphic adenoma, adenocarcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma."
      },
      "child_count": 26,
      "reference_id": "MONDO:0000521"
    },
    {
      "id": 6712,
      "label": "adenocarcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        21312
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-0386",
          "DOID:299",
          "EFO:0000228",
          "ICDO:8140/3",
          "MEDGEN:122",
          "MESH:D000230",
          "NCIT:C2852",
          "ONCOTREE:ADNOS",
          "SCTID:443961001",
          "UMLS:C0001418"
        ],
        "synonyms": [
          "adenocarcinoma",
          "adenocarcinoma NOS (morphologic abnormality)",
          "adenocarcinoma, malignant",
          "adenocarcinoma, no subtype (morphologic abnormality)",
          "adenocarcinomas",
          "ADNOS"
        ],
        "definition": "A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma."
      },
      "child_count": 128,
      "reference_id": "MONDO:0004970"
    },
    {
      "id": 7027,
      "label": "skin basal cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4707,
        20201
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-2719",
          "DOID:2513",
          "HP:0002671",
          "ICDO:8090/3",
          "MEDGEN:1648304",
          "NCIT:C2921",
          "ONCOTREE:BCC",
          "SCTID:254701007",
          "UMLS:C4721806"
        ],
        "synonyms": [
          "BCC",
          "basal cell cancer",
          "basal cell carcinoma",
          "basal cell tumor",
          "basal cell tumour",
          "basal cell tumour (morphologic abnormality)",
          "malignant basal cell tumour",
          "malignant basal cell tumour (morphologic abnormality)",
          "basal cell carcinoma of skin",
          "basal cell carcinoma of the skin",
          "basal cell epithelioma",
          "basal cell skin carcinoma",
          "skin basal cell cancer",
          "skin basal cell carcinoma",
          "epithelioma basal cell"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas."
      },
      "child_count": 50,
      "reference_id": "MONDO:0005341"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2972,
      "label": "salivary gland carcinoma"
    },
    {
      "id": 6712,
      "label": "adenocarcinoma"
    },
    {
      "id": 7027,
      "label": "skin basal cell carcinoma"
    }
  ]
}