{
  "id": 7922,
  "label": "salivary gland carcinoma ex pleomorphic adenoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006403",
  "properties": {
    "xrefs": [
      "DOID:297",
      "EFO:1000516",
      "GARD:0027752",
      "MEDGEN:274190",
      "NCIT:C40410",
      "UMLS:C1519172"
    ],
    "synonyms": [
      "saliva-secreting gland carcinoma ex pleomorphic adenoma",
      "salivary gland carcinoma ex pleomorphic adenoma",
      "pleomorphic adenoma carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      }
    ],
    "definition": "A carcinoma that arises from a pleomorphic adenoma in the salivary glands. It usually originates in the parotid gland. Patients usually present with a history of a long-standing tumor mass which grew rapidly in the past few months. Patients with non-invasive or minimally invasive carcinoma have an excellent prognosis. In cases where there is invasion of the surrounding tissues, the clinical course is aggressive."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 2972,
      "label": "salivary gland carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6453,
        23483
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050904",
          "GARD:0027535",
          "MEDGEN:215302",
          "NANDO:2200076",
          "NCIT:C9272",
          "ONCOTREE:SACA",
          "UMLS:C0948750"
        ],
        "synonyms": [
          "salivary gland cancer",
          "carcinoma of saliva-secreting gland",
          "carcinoma of salivary gland",
          "carcinoma of the salivary gland",
          "saliva-secreting gland carcinoma",
          "salivary gland carcinoma",
          "salivary carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A carcinoma that arises from the major or minor salivary glands. Representative examples include carcinoma ex pleomorphic adenoma, adenocarcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma."
      },
      "child_count": 26,
      "reference_id": "MONDO:0000521"
    },
    {
      "id": 4552,
      "label": "carcinoma ex pleomorphic adenoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4477,
        6734,
        7464
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8941/3",
          "MEDGEN:87486",
          "NCIT:C4397",
          "UMLS:C0344460"
        ],
        "synonyms": [
          "carcinoma ex pleomorphic adenoma",
          "carcinoma ex pleomorphic adenoma (morphologic abnormality)",
          "carcinoma in pleomorphic adenoma"
        ],
        "definition": "A carcinoma arising in a pre-existing pleomorphic adenoma. It most often occurs in the parotid gland and less often in the submandibular gland and minor salivary gland. Patients usually present with a history of a long-standing mass which recently had undergone rapid growth. The prognosis depends on the invasiveness of the malignant component. Patients with non-invasive or minimally invasive tumors usually have a good prognosis following surgical resection. Invasive tumors are usually aggressive and are associated with recurrences and metastases."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002472"
    }
  ],
  "children": [
    {
      "id": 7828,
      "label": "major salivary gland carcinoma ex pleomorphic adenoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7827,
        7922
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000345",
          "GARD:0027746",
          "MEDGEN:233655",
          "NCIT:C5975",
          "UMLS:C1334550"
        ],
        "synonyms": [
          "carcinoma ex pleomorphic adenoma of Major salivary gland",
          "carcinoma ex pleomorphic adenoma of the Major salivary gland",
          "major salivary gland carcinoma ex pleomorphic adenoma",
          "major salivary gland salivary gland carcinoma ex pleomorphic adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A carcinoma that arises from a pleomorphic adenoma in the major salivary glands. It usually originates in the parotid gland. Patients usually present with a history of a long-standing tumor mass which grew rapidly in the past few months. Patients with non-invasive or minimally invasive carcinoma have an excellent prognosis. In cases where there is invasion of the surrounding tissues, the clinical course is aggressive."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006285"
    }
  ],
  "roots": [
    {
      "id": 2972,
      "label": "salivary gland carcinoma"
    },
    {
      "id": 4552,
      "label": "carcinoma ex pleomorphic adenoma"
    }
  ]
}