{
  "id": 7935,
  "label": "small intestinal enteropathy-associated T-cell lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006418",
  "properties": {
    "xrefs": [
      "EFO:1000535",
      "GARD:0024406",
      "MEDGEN:275445",
      "NCIT:C39610",
      "UMLS:C1519371"
    ],
    "synonyms": [
      "enteropathy-associated T-cell lymphoma of small intestine",
      "small intestinal EATL",
      "small intestinal enteropathy-type T-cell lymphoma",
      "small intestine enteropathy-associated T-cell lymphoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "An enteropathy-associated T-cell lymphoma arising from the small intestine, most commonly the jejunum or ileum. Patients usually present with abdominal pain, often associated with intestinal perforation. There is often a history of celiac disease. The lymphoma cells are usually medium-sized to large and form an ulcerating mucosal lesion with invasion of the small intestinal wall. Villous atrophy is present in the adjacent small intestinal mucosa. In a minority of cases the lymphoma cells are medium-sized and form a monomorphic infiltrate."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3028,
      "label": "immune system cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        6778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060083"
        ],
        "synonyms": [
          "cancer of immune system",
          "immune system cancer",
          "malignant immune system neoplasm",
          "malignant neoplasm of immune system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the immune system"
      },
      "child_count": 50,
      "reference_id": "MONDO:0000621"
    },
    {
      "id": 4030,
      "label": "small intestine lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3225,
        6479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13996",
          "GARD:0023024",
          "ICD9:202.80",
          "MEDGEN:82986",
          "NCIT:C4007",
          "SCTID:449074003",
          "UMLS:C0278805"
        ],
        "synonyms": [
          "lymphoma of small bowel",
          "lymphoma of small intestine",
          "lymphoma of the small bowel",
          "lymphoma of the small intestine",
          "primary small intestinal lymphoma",
          "small bowel lymphoma",
          "small intestinal lymphoma",
          "small intestine lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A non-Hodgkin or Hodgkin lymphoma that arises from the small intestine."
      },
      "child_count": 8,
      "reference_id": "MONDO:0001852"
    },
    {
      "id": 6569,
      "label": "leukocyte disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6778,
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9500",
          "ICD9:288",
          "ICD9:288.9",
          "MEDGEN:7325",
          "MESH:D007960",
          "SCTID:54097007",
          "UMLS:C0023510"
        ],
        "synonyms": [
          "disease of leukocyte",
          "disease or disorder of leukocyte",
          "disorder of leukocyte",
          "disorder, leukocyte",
          "disorders, leukocyte",
          "leukocyte disease",
          "leukocyte disease or disorder",
          "leukocyte disorder",
          "white blood cell disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A disease involving leukocytes."
      },
      "child_count": 46,
      "reference_id": "MONDO:0004805"
    },
    {
      "id": 19298,
      "label": "enteropathy-associated T-cell lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16517
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009809",
          "ICD10CM:C86.2",
          "ICD9:202.70",
          "ICDO:9717/3",
          "MEDGEN:96832",
          "MESH:D058527",
          "MedDRA:10022703",
          "NCIT:C4737",
          "ONCOTREE:EATL",
          "Orphanet:86880",
          "SCTID:277654008",
          "UMLS:C0456889",
          "icd11.foundation:958629729"
        ],
        "synonyms": [
          "EATL",
          "EATL, type I",
          "ETTL",
          "enteropathy associated T-cell lymphoma",
          "enteropathy-associated T-cell lymphoma, type I",
          "enteropathy-type T-cell lymphoma",
          "intestinal T-cell lymphoma",
          "EATCL",
          "high-grade pleomorphic peripheral T-cell lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An uncommon mature T-cell lymphoma of intraepithelial lymphocytes. It usually arises from the small intestine, most commonly the jejunum or ileum. Other less frequent primary anatomic sites include the duodenum, stomach, colon, or outside the gastrointestinal tract. It is seen with increased frequency in regions with a high prevalence of celiac disease."
      },
      "child_count": 1,
      "reference_id": "MONDO:0019473"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3028,
      "label": "immune system cancer"
    },
    {
      "id": 4030,
      "label": "small intestine lymphoma"
    },
    {
      "id": 6569,
      "label": "leukocyte disorder"
    },
    {
      "id": 19298,
      "label": "enteropathy-associated T-cell lymphoma"
    }
  ]
}