{
  "id": 7967,
  "label": "thyroid gland squamous cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006467",
  "properties": {
    "xrefs": [
      "EFO:1000594",
      "GARD:0024423",
      "MEDGEN:328050",
      "NCIT:C46008",
      "UMLS:C1710177"
    ],
    "synonyms": [
      "squamous cell thyroid gland carcinoma",
      "thyroid gland squamous cell carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A rapidly growing primary carcinoma of the thyroid gland composed of malignant squamous cells. The clinical course is usually aggressive."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6823,
      "label": "squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4600,
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1749",
          "EFO:0000707",
          "ICDO:8070/3",
          "MEDGEN:2874",
          "MESH:D002294",
          "NCIT:C2929",
          "SCTID:402815007",
          "UMLS:C0007137"
        ],
        "synonyms": [
          "carcinoma, squamous cell, malignant",
          "epidermoid carcinoma",
          "epidermoid cell cancer",
          "malignant epidermoid cell neoplasm",
          "malignant epidermoid cell tumor",
          "malignant epidermoid cell tumour",
          "malignant squamous cell neoplasm",
          "malignant squamous cell tumor",
          "malignant squamous cell tumour",
          "squamous carcinoma",
          "squamous cell cancer",
          "squamous cell carcinoma",
          "squamous cell carcinoma (morphologic abnormality)",
          "squamous cell carcinoma NOS (morphologic abnormality)",
          "squamous cell epithelioma"
        ],
        "definition": "A carcinoma arising from squamous epithelial cells. Morphologically, it is characterized by the proliferation of atypical, often pleomorphic squamous cells. Squamous cell carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Well differentiated carcinomas are usually associated with keratin production and the presence of intercellular bridges between adjacent cells. Representative examples are lung squamous cell carcinoma, skin squamous cell carcinoma, and cervical squamous cell carcinoma."
      },
      "child_count": 78,
      "reference_id": "MONDO:0005096"
    },
    {
      "id": 16049,
      "label": "thyroid gland carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4245,
        6734
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3963",
          "EFO:0002892",
          "GARD:0019763",
          "HP:0002890",
          "MEDGEN:107811",
          "MedDRA:10007476",
          "NANDO:2200074",
          "NCIT:C4815",
          "Orphanet:100088",
          "SCTID:448216007",
          "UMLS:C0549473"
        ],
        "synonyms": [
          "cancer of the thyroid",
          "cancer of thyroid",
          "head and neck cancer, thyroid",
          "thyroid cancer",
          "thyroid gland cancer",
          "carcinoma of the thyroid",
          "carcinoma of the thyroid gland",
          "carcinoma of thyroid",
          "carcinoma of thyroid gland",
          "thyroid carcinoma",
          "thyroid gland carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma arising from the thyroid gland. It is usually an adenocarcinoma and includes the following main subtypes: follicular, papillary, medullary, poorly differentiated, and anaplastic."
      },
      "child_count": 22,
      "reference_id": "MONDO:0015075"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6823,
      "label": "squamous cell carcinoma"
    },
    {
      "id": 16049,
      "label": "thyroid gland carcinoma"
    }
  ]
}