{
  "id": 7978,
  "label": "ureter carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006481",
  "properties": {
    "xrefs": [
      "DOID:4939",
      "EFO:1000609",
      "MEDGEN:109002",
      "NCIT:C8993",
      "SCTID:448864006",
      "UMLS:C0600079"
    ],
    "synonyms": [
      "ureter cancer",
      "carcinoma of the ureter",
      "carcinoma of ureter",
      "ureter carcinoma",
      "ureteral carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A carcinoma that arises from epithelial cells of the ureter."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    },
    {
      "id": 9910,
      "label": "ureter cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7836,
        20350
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11819",
          "ICD10CM:C66",
          "ICD9:189.2",
          "MEDGEN:102281",
          "MESH:D014516",
          "NCIT:C7543",
          "OMIM:191600",
          "SCTID:363458004",
          "UMLS:C0153619"
        ],
        "synonyms": [
          "cancer of ureter",
          "malignant neoplasm of the ureter",
          "malignant neoplasm of ureter",
          "malignant tumor of the ureter",
          "malignant tumor of ureter",
          "malignant tumour of the ureter",
          "malignant ureter neoplasm",
          "malignant ureter tumor",
          "malignant ureter tumour",
          "malignant ureteral neoplasm",
          "malignant ureteral tumor",
          "malignant ureteral tumour",
          "ureter cancer",
          "ureter, cancer OF"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the ureter"
      },
      "child_count": 6,
      "reference_id": "MONDO:0008627"
    }
  ],
  "children": [
    {
      "id": 4139,
      "label": "regional ureteric cancer",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7978
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14491",
          "MEDGEN:167733",
          "NCIT:C9356",
          "UMLS:C0854921"
        ],
        "synonyms": [
          "regional malignant ureteral tumour",
          "regional ureter carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Carcinoma of the ureter without spread to any other region."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001978"
    },
    {
      "id": 5171,
      "label": "ureter adenocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6712,
        7978
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4938",
          "MEDGEN:234456",
          "NCIT:C6155",
          "UMLS:C1336873"
        ],
        "synonyms": [
          "adenocarcinoma of the ureter",
          "adenocarcinoma of ureter",
          "ureter adenocarcinoma",
          "ureteral adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A carcinoma that arises from glandular epithelial cells of the ureter"
      },
      "child_count": 0,
      "reference_id": "MONDO:0003216"
    },
    {
      "id": 5416,
      "label": "ureter squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6823,
        7978
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5539",
          "MEDGEN:237032",
          "NCIT:C6154",
          "UMLS:C1336879"
        ],
        "synonyms": [
          "epidermoid carcinoma of the ureter",
          "epidermoid carcinoma of ureter",
          "squamous cell carcinoma of the ureter",
          "squamous cell carcinoma of ureter",
          "ureter epidermoid carcinoma",
          "ureter squamous cell carcinoma",
          "ureteral epidermoid carcinoma",
          "ureteral squamous cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A rare squamous cell carcinoma that arises from the ureter."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003502"
    },
    {
      "id": 5874,
      "label": "ureter transitional cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7978,
        20068
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6888",
          "GARD:0023785",
          "MEDGEN:108291",
          "NCIT:C4830",
          "SCTID:300988009",
          "UMLS:C0577692"
        ],
        "synonyms": [
          "transitional cell carcinoma of the ureter",
          "transitional cell carcinoma of ureter",
          "ureter transitional cell carcinoma",
          "ureter urothelial cancer",
          "ureter urothelial carcinoma",
          "ureteral transitional cell carcinoma",
          "ureteral urothelial cell carcinoma",
          "urothelial cell carcinoma of the ureter",
          "urothelial cell carcinoma of ureter"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the transitional epithelium of the ureter. It is associated with tobacco use and usually presents with gross or microscopic hematuria."
      },
      "child_count": 2,
      "reference_id": "MONDO:0004030"
    },
    {
      "id": 7979,
      "label": "ureter small cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2894,
        7978
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6886",
          "GARD:0024430",
          "MEDGEN:234971",
          "NCIT:C6176",
          "UMLS:C1336878"
        ],
        "synonyms": [
          "small cell carcinoma of the ureter",
          "small cell carcinoma of ureter",
          "ureter small cell carcinoma",
          "ureteral small cell carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare carcinoma that arises from the ureter. It is characterized by the presence of small neuroendocrine cells. The prognosis is poor."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006482"
    },
    {
      "id": 20475,
      "label": "carcinoma in situ of ureter",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6433,
        7978
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:233.9",
          "MEDGEN:1660901",
          "NCIT:C4529",
          "SCTID:92782006",
          "UMLS:C4721448"
        ],
        "synonyms": [
          "carcinoma in situ of the ureter",
          "carcinoma in situ of ureter",
          "stage 0 ureter carcinoma",
          "stage 0is carcinoma of the ureter",
          "stage 0is carcinoma of ureter",
          "stage 0is ureter cancer",
          "stage 0is ureter cancer aJCC v7",
          "stage 0is ureter carcinoma",
          "stage 0is ureter urothelial cancer",
          "stage 0is ureter urothelial carcinoma",
          "stage 0is ureter urothelial carcinoma aJCC v7",
          "stage 0is ureteral carcinoma",
          "ureter cancer stage 0is",
          "ureter carcinoma in situ",
          "ureter in situ carcinoma",
          "ureteral carcinoma in situ"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A in situ carcinoma that involves the ureter."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021284"
    }
  ],
  "roots": [
    {
      "id": 6734,
      "label": "carcinoma"
    },
    {
      "id": 9910,
      "label": "ureter cancer"
    }
  ]
}