{
  "id": 7989,
  "label": "Warthin tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006493",
  "properties": {
    "xrefs": [
      "EFO:1000625",
      "ICDO:8561/0",
      "MEDGEN:124",
      "MESH:D000235",
      "NCIT:C2854",
      "SCTID:422470007",
      "UMLS:C0001429"
    ],
    "synonyms": [
      "Warthin tumor",
      "Warthin's tumor",
      "Warthin's tumour",
      "adenolymphoma",
      "papillary cystadenoma lymphomatosum",
      "papillary cystadenoma lymphomatosum (formerly)"
    ],
    "categories": [
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      }
    ],
    "definition": "An adenoma characterized by an oncocytic, often papillary, epithelial component, dense lymphoid stroma, and cystic spaces. It occurs primarily in the parotid gland, and is the second most common benign parotid salivary gland tumor. A strong association with smoking has been reported. It typically presents as a painless swelling in the lower portion of the parotid gland."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7737,
      "label": "digestive system adenoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6714,
        20434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4147",
          "EFO:1000217",
          "MEDGEN:184920",
          "NCIT:C36207",
          "UMLS:C0948101"
        ],
        "synonyms": [
          "digestive system adenoma",
          "digestive tract adenoma",
          "gastrointestinal adenoma"
        ],
        "definition": "A sporadic or less frequently familial neoplasm, arising from the glandular epithelium of the stomach, small intestine, biliary tract, colon, and rectum. It is a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger adenomas with severe dysplastic changes (sometimes called carcinoma in situ) carry a higher risk of progressing to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. Familial adenomas tend to be multifocal and carry a higher risk of malignant transformation."
      },
      "child_count": 12,
      "reference_id": "MONDO:0006180"
    },
    {
      "id": 20582,
      "label": "benign neoplasm of salivary gland",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6887,
        20523
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:83857",
          "NCIT:C4600",
          "SCTID:255154009",
          "UMLS:C0347206"
        ],
        "synonyms": [
          "benign neoplasm of the salivary gland",
          "benign salivary gland neoplasm",
          "benign salivary gland tumor",
          "benign salivary gland tumour",
          "benign tumor of salivary gland",
          "benign tumor of the salivary gland",
          "benign tumour of salivary gland",
          "benign tumour of the salivary gland",
          "saliva-secreting gland benign neoplasm",
          "salivary gland neoplasm, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the saliva-secreting gland."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021460"
    },
    {
      "id": 22952,
      "label": "benign epithelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6887,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8010/0",
          "ICDO:8011/0",
          "MEDGEN:90747",
          "NCIT:C4092",
          "UMLS:C0334232"
        ],
        "synonyms": [
          "benign epithelial neoplasm",
          "benign epithelial tumor",
          "benign epithelial tumour",
          "benign epithelioma",
          "benign neoplasm of epithelium",
          "benign neoplasm of the epithelium",
          "benign tumor of epithelium",
          "benign tumor of the epithelium",
          "benign tumour of epithelium",
          "benign tumour of the epithelium",
          "epithelial neoplasm, benign",
          "epithelioma, benign"
        ],
        "definition": "A neoplasm arising from the epithelial cells. It is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign epithelial neoplasms remain confined to the original site of growth and only rarely metastasize to other anatomic sites."
      },
      "child_count": 50,
      "reference_id": "MONDO:0036976"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7737,
      "label": "digestive system adenoma"
    },
    {
      "id": 20582,
      "label": "benign neoplasm of salivary gland"
    },
    {
      "id": 22952,
      "label": "benign epithelial neoplasm"
    }
  ]
}