{
  "id": 7990,
  "label": "palsy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006496",
  "properties": {
    "xrefs": [
      "EFO:1000631",
      "ICD10CM:G80-G83",
      "MEDGEN:854494",
      "MESH:D010243",
      "UMLS:C3887651",
      "Wikipedia:Palsy"
    ],
    "synonyms": [
      "Plegia",
      "Plegias"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 10,
  "parents": [
    {
      "id": 4657,
      "label": "central nervous system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6799
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:331",
          "EFO:0009386",
          "MEDGEN:892343",
          "MESH:D002493",
          "NCIT:C2934",
          "SCTID:23853001",
          "UMLS:C4021765"
        ],
        "synonyms": [
          "CNS disorder",
          "central nervous disease",
          "central nervous system disease",
          "central nervous system disease or disorder",
          "central nervous system disorder",
          "disease of central nervous system",
          "disease of the central nervous system",
          "disease or disorder of central nervous system",
          "disorder of central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disease involving the central nervous system."
      },
      "child_count": 19,
      "reference_id": "MONDO:0002602"
    }
  ],
  "children": [
    {
      "id": 3414,
      "label": "hemiplegia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7990
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10969",
          "EFO:0009453",
          "ICD10WHO:G81",
          "ICD9:343.4",
          "MEDGEN:9196",
          "MESH:D006429",
          "SCTID:1593000",
          "UMLS:C0018991",
          "icd11.foundation:1641958762"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Severe or complete loss of motor function on one side of the body. This condition is usually caused by brain diseases that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, brain stem lesions; cervical spinal cord diseases; peripheral nervous system diseases; and other conditions may manifest as hemiplegia. The term hemiparesis (see paresis) refers to mild to moderate weakness involving one side of the body."
      },
      "child_count": 1,
      "reference_id": "MONDO:0001170"
    },
    {
      "id": 3789,
      "label": "quadriplegia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7990
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12835",
          "EFO:0009684",
          "ICD10CM:G82.5",
          "ICD9:344.00",
          "ICD9:344.09",
          "MEDGEN:19617",
          "MESH:D011782",
          "NCIT:C50721",
          "SCTID:11538006",
          "UMLS:C0034372"
        ],
        "synonyms": [
          "bilateral diplegia",
          "tetraplegia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Paralysis of all four limbs."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001590"
    },
    {
      "id": 4015,
      "label": "facial paralysis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7990
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13934",
          "MEDGEN:5101",
          "MESH:D005158",
          "SCTID:280816001",
          "UMLS:C0015469"
        ],
        "synonyms": [
          "face palsy",
          "palsy of face"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Severe or complete loss of facial muscle motor function. This condition may result from central or peripheral lesions. Damage to CNS motor pathways from the cerebral cortex to the facial nuclei in the pons leads to facial weakness that generally spares the forehead muscles. facial nerve diseases generally results in generalized hemifacial weakness. neuromuscular junction diseases and muscular diseases may also cause facial paralysis or paresis."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001835"
    },
    {
      "id": 5353,
      "label": "ophthalmoplegia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3785,
        7990
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:539",
          "ICD9:378.56",
          "MEDGEN:45205",
          "MESH:D009886",
          "SCTID:78097002",
          "UMLS:C0029089",
          "icd11.foundation:1848588735"
        ],
        "synonyms": [
          "oculomotor paralysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Weakness or paralysis of at least one of the muscles controlling the movement of the eye. It results from degeneration of the muscles or the neural pathways involved in the eye movement. Representative disorders causing ophthalmoplegia include ocular myopathies and multiple sclerosis."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003425"
    },
    {
      "id": 5637,
      "label": "paraplegia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7990
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:607",
          "EFO:0009679",
          "ICD10CM:G82.2",
          "ICD9:344.1",
          "MEDGEN:45323",
          "MESH:D010264",
          "NCIT:C50687",
          "SCTID:60389000",
          "UMLS:C0030486",
          "icd11.foundation:1212533558"
        ],
        "synonyms": [
          "severe or complete loss of motor function in the lower extremities and lower portions of the trunk"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Complete paralysis of the lower half of the body including both legs, often caused by damage to the spinal cord."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003757"
    },
    {
      "id": 7991,
      "label": "cerebral palsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7990,
        23499
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:0723-4729",
          "DOID:1969",
          "EFO:1000632",
          "HP:0100021",
          "ICD10CM:G80",
          "ICD10WHO:G80",
          "ICD9:343.8",
          "ICD9:343.9",
          "MEDGEN:854",
          "MESH:D002547",
          "NCIT:C34460",
          "SCTID:128188000",
          "UMLS:C0007789",
          "icd11.foundation:76906748"
        ],
        "synonyms": [
          "infantile cerebral palsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain."
      },
      "child_count": 10,
      "reference_id": "MONDO:0006497"
    },
    {
      "id": 10155,
      "label": "progressive bulbar palsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4811,
        7209,
        7990,
        10156
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:681",
          "EFO:0003783",
          "GARD:0010928",
          "ICD10CM:G12.22",
          "ICD9:335.22",
          "MEDGEN:18290",
          "MESH:D010244",
          "NCIT:C85026",
          "SCTID:54304004",
          "UMLS:C0030442",
          "icd11.foundation:1143049440"
        ],
        "synonyms": [
          "Fazio-Londe disease",
          "bulbar palsy, progressive, of childhood",
          "progressive bulbar atrophy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Progressive bulbar palsy involves the brain stem. The brain stem is the part of the brain needed for swallowing, speaking, chewing, and other functions. Signs and symptoms of progressive bulbar palsy include difficulty swallowing, weak jaw and facial muscles, progressive loss of speech, and weakening of the tongue. Additional symptoms include less prominent weakness in the arms and legs, and outbursts of laughing or crying (called emotional lability). Progressive bulbar palsy is considered a variant form of amyotrophic lateral sclerosis (ALS). Many people with progressive bulbar palsy later develop ALS. While there is no cure for progressive bulbar palsy or for ALS, doctors can treat symptoms."
      },
      "child_count": 4,
      "reference_id": "MONDO:0008890"
    },
    {
      "id": 21115,
      "label": "klumpke's paralysis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7990
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0003123",
          "MEDGEN:124376",
          "NCIT:C116724",
          "SCTID:83886009",
          "UMLS:C0270898"
        ],
        "synonyms": [
          "klumpke's paralysis",
          "klumpke-dC)jerine paralysis",
          "Dejerine Klumpke Palsy",
          "Dejerine-Klumpke Palsy",
          "Dejerine-Klumpke palsy",
          "Klumpke Palsy",
          "Klumpke Paralysis",
          "Klumpke paralysis",
          "Klumpke's Palsy",
          "Klumpke's palsy",
          "Klumpke's paralysis",
          "Klumpke-DC)jerine brachial plexus injury",
          "Klumpke-DC)jerine paralysis",
          "Klumpke-Dejerine paralysis",
          "Klumpkes Palsy",
          "Lower Brachial Plexus Palsy",
          "Lower brachial plexus palsy",
          "Palsy, Dejerine-Klumpke",
          "Palsy, Klumpke's",
          "Paralysis of the Lower Brachial Plexus",
          "Paralysis, Klumpke",
          "klumpke paralysis",
          "klumpke's palsy",
          "klumpke-dC)jerine brachial plexus injury",
          "klumpke-dejerine paralysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Klumpke paralysis is a type of brachial palsy in newborns. Signs and symptoms include weakness and loss of movement of the arm and hand. Some babies experience drooping of the eyelid on the opposite side of the face as well. This symptom may also be referred to as Horner syndrome. Klumpke paralysis is caused by an injury to the nerves of the brachial plexus which may result from a difficult delivery. This injury can cause a stretching (neuropraxia), tearing (called avulsion when the tear is at the spine, and rupture when it is not), or scarring (neuroma) of the brachial plexus nerves. Most infants with Klumpke paralysis have the more mild form of injury (neuropraxia) and often recover within 6 months."
      },
      "child_count": 0,
      "reference_id": "MONDO:0023054"
    },
    {
      "id": 23246,
      "label": "respiratory paralysis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7354,
        7990,
        20352
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025868",
          "MEDGEN:19748",
          "MESH:D012133",
          "SCTID:64228003",
          "UMLS:C0035232"
        ],
        "synonyms": [
          "paralysis of diaphragm",
          "diaphragmatic paralysis",
          "muscle paralysis, respiratory",
          "muscle paralyzes, respiratory",
          "paralysis, diaphragmatic",
          "paralysis, respiratory",
          "paralysis, respiratory muscle",
          "respiratory muscle paralysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Complete or severe weakness of the muscles of respiration. This condition may be associated with motor neuron diseases; peripheral nerve diseases; neuromuscular junction diseases; spinal cord diseases; injury to the phrenic nerve; and other disorders."
      },
      "child_count": 0,
      "reference_id": "MONDO:0043775"
    },
    {
      "id": 24695,
      "label": "Erb palsy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6367,
        7990
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027389",
          "ICD10CM:P14.0",
          "MEDGEN:78746",
          "SCTID:78141002",
          "UMLS:C0270897"
        ],
        "synonyms": [
          "Erb's palsy",
          "Erb-Duchenne paralysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A palsy characterized by a paralysis of the arm caused by an injury to the upper group of the main nerves supplying it, specifically the upper trunk C5-C6 of the brachial plexus. Erb palsy most commonly, though not exclusively, arises as a result of an injury sustained during birth."
      },
      "child_count": 0,
      "reference_id": "MONDO:0700303"
    }
  ],
  "roots": [
    {
      "id": 4657,
      "label": "central nervous system disorder"
    }
  ]
}