{
  "id": 8006,
  "label": "rectal cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006519",
  "properties": {
    "xrefs": [
      "DOID:1993",
      "EFO:1000657",
      "ICD10CM:C20",
      "ICD9:154.1",
      "MEDGEN:181763",
      "NCIT:C7418",
      "SCTID:363351006",
      "UMLS:C0949022",
      "icd11.foundation:1113099195"
    ],
    "synonyms": [
      "carcinoma of rectum",
      "carcinoma of the rectum",
      "cancer of rectum",
      "malignant neoplasm of rectum",
      "malignant neoplasm of the rectum",
      "malignant rectal neoplasm",
      "malignant rectal tumor",
      "malignant rectal tumour",
      "malignant rectum neoplasm",
      "malignant rectum tumour",
      "malignant tumor of rectum",
      "malignant tumor of the rectum",
      "malignant tumour of rectum",
      "malignant tumour of the rectum",
      "rectal cancer",
      "rectum cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A primary or metastatic malignant neoplasm that affects the rectum. Representative examples include carcinoma, lymphoma, and sarcoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 4291,
      "label": "rectal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3792,
        7022
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1984",
          "MEDGEN:11148",
          "MESH:D012004",
          "NCIT:C3350",
          "SCTID:126847008",
          "UMLS:C0034885"
        ],
        "synonyms": [
          "neoplasm of rectum",
          "neoplasm of the rectum",
          "rectal neoplasm",
          "rectal tumor",
          "rectal tumour",
          "rectum neoplasm (disease)",
          "rectum tumor",
          "rectum tumour",
          "tumor of rectum",
          "tumor of the rectum",
          "tumour of rectum",
          "tumour of the rectum"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm that affects the rectum. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Rectal adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002165"
    },
    {
      "id": 7221,
      "label": "colorectal cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7022,
        7430
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5672",
          "DOID:9256",
          "MEDGEN:83428",
          "NCIT:C4978",
          "OMIM:114500",
          "Orphanet:466667",
          "SCTID:363510005",
          "UMLS:C0346629"
        ],
        "synonyms": [
          "cancer of colorectum",
          "cancer of large bowel",
          "cancer of large intestine",
          "cancer of the large bowel",
          "colon cancer, advanced, somatic",
          "colon cancer, somatic",
          "colorectal cancer",
          "colorectal cancer with chromosomal instability, somatic",
          "colorectal cancer, autosomal dominant, somatic mutation",
          "colorectal cancer, somatic",
          "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation",
          "colorectum cancer",
          "malignant colorectal neoplasm",
          "malignant colorectal tumor",
          "malignant colorectal tumour",
          "malignant colorectum neoplasm",
          "malignant large bowel neoplasm",
          "malignant large bowel tumor",
          "malignant large bowel tumour",
          "malignant large intestine neoplasm",
          "malignant large intestine tumor",
          "malignant large intestine tumour",
          "malignant neoplasm of colorectum",
          "malignant neoplasm of large bowel",
          "malignant neoplasm of large intestine",
          "malignant neoplasm of the large bowel",
          "malignant neoplasm of the large intestine",
          "malignant tumor of large bowel",
          "malignant tumor of large intestine",
          "malignant tumor of the large bowel",
          "malignant tumor of the large intestine",
          "malignant tumour of large bowel",
          "malignant tumour of large intestine",
          "malignant tumour of the large bowel",
          "malignant tumour of the large intestine",
          "CRC",
          "colon cancer",
          "colon cancer, susceptibility to, autosomal dominant, somatic mutation",
          "large intestine cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005575"
    }
  ],
  "children": [
    {
      "id": 4054,
      "label": "anus cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5037,
        8006
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14110",
          "GARD:0009300",
          "ICD9:154.3",
          "MEDGEN:56303",
          "NCIT:C7379",
          "UMLS:C0153446"
        ],
        "synonyms": [
          "anus cancer",
          "cancer of anus",
          "malignant anal neoplasm",
          "malignant anal tumor",
          "malignant anal tumour",
          "malignant anus neoplasm",
          "malignant neoplasm of anus",
          "malignant neoplasm of the anus",
          "malignant tumor of anus",
          "malignant tumor of the anus",
          "malignant tumour of anus",
          "malignant tumour of the anus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the anus"
      },
      "child_count": 8,
      "reference_id": "MONDO:0001879"
    },
    {
      "id": 4292,
      "label": "rectum lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8006,
        21564
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1988",
          "GARD:0023082",
          "MEDGEN:233393",
          "NCIT:C5553",
          "UMLS:C1335685"
        ],
        "synonyms": [
          "lymphoma of rectum",
          "lymphoma of the rectum",
          "primary rectal lymphoma",
          "rectal lymphoma",
          "rectum lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An extranodal lymphoma that arises from the rectum. The majority are B-cell non-Hodgkin lymphomas."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002166"
    },
    {
      "id": 4293,
      "label": "rectum malignant melanoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8006,
        23550
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1992",
          "MEDGEN:87605",
          "NCIT:C4640",
          "SCTID:276822007",
          "UMLS:C0349539"
        ],
        "synonyms": [
          "malignant melanoma of rectum",
          "malignant melanoma of the rectum",
          "melanoma (disease) of rectum",
          "melanoma of rectum",
          "melanoma of the rectum",
          "rectal malignant melanoma",
          "rectal melanoma",
          "rectum melanoma",
          "rectum melanoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An aggressive malignant melanocytic neoplasm that arises from the rectum."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002167"
    },
    {
      "id": 4294,
      "label": "rectum sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        8006
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1995",
          "MEDGEN:277577",
          "NCIT:C5548",
          "UMLS:C1335688"
        ],
        "synonyms": [
          "rectal sarcoma",
          "rectum sarcoma",
          "sarcoma of rectum",
          "sarcoma of the rectum"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant soft tissue neoplasm that arises from the rectum. Representative examples include angiosarcoma, Kaposi sarcoma, and leiomyosarcoma."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002168"
    },
    {
      "id": 4513,
      "label": "rectosigmoid junction cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3679,
        4511,
        8006
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2782",
          "ICD10CM:C19",
          "ICD9:154.0",
          "MEDGEN:57558",
          "NCIT:C7420",
          "SCTID:363414004",
          "UMLS:C0153443",
          "icd11.foundation:774170412"
        ],
        "synonyms": [
          "cancer of rectosigmoid junction",
          "malignant neoplasm of rectosigmoid",
          "malignant neoplasm of rectosigmoid junction",
          "malignant neoplasm of the rectosigmoid junction",
          "malignant rectosigmoid junction neoplasm",
          "malignant rectosigmoid neoplasm",
          "malignant rectosigmoid tumor",
          "malignant rectosigmoid tumour",
          "malignant tumor of rectosigmoid junction",
          "malignant tumor of the rectosigmoid junction",
          "malignant tumour of rectosigmoid junction",
          "malignant tumour of the rectosigmoid junction",
          "rectosigmoid junction cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm that affects the rectosigmoid area. Representative examples include carcinoma, lymphoma, and sarcoma."
      },
      "child_count": 3,
      "reference_id": "MONDO:0002425"
    },
    {
      "id": 23485,
      "label": "rectal carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8006,
        21360,
        21431
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:40100",
          "NCIT:C9382",
          "UMLS:C0007113"
        ],
        "synonyms": [
          "cancer of rectum",
          "cancer of the rectum",
          "rectal cancer",
          "carcinoma of rectum",
          "carcinoma of the rectum",
          "rectal carcinoma",
          "rectum carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A malignant epithelial neoplasm that arises from the rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas."
      },
      "child_count": 18,
      "reference_id": "MONDO:0044937"
    }
  ],
  "roots": [
    {
      "id": 4291,
      "label": "rectal neoplasm"
    },
    {
      "id": 7221,
      "label": "colorectal cancer"
    }
  ]
}