{
  "id": 8054,
  "label": "lipomatosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006574",
  "properties": {
    "xrefs": [
      "DOID:3153",
      "EFO:1000728",
      "ICD9:272.8",
      "MEDGEN:9781",
      "MESH:D008068",
      "NCIT:C3193",
      "SCTID:402693001",
      "UMLS:C0023801",
      "Wikipedia:Lipomatosis"
    ],
    "synonyms": [
      "Launois-Bensaude syndrome",
      "Madelung disease",
      "Madelung's disease",
      "lipomatosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A neoplastic process characterized by diffuse overgrowth of mature adipose tissue."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 23492,
      "label": "benign lipomatous neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3054,
        20521
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:D17",
          "ICD10WHO:D17",
          "MEDGEN:91084",
          "NCIT:C4502",
          "UMLS:C0346118",
          "icd11.foundation:226447034"
        ],
        "synonyms": [
          "adipose tissue benign connective and soft tissue neoplasm",
          "benign adipose tissue neoplasm",
          "benign adipose tissue tumor",
          "benign adipose tissue tumour",
          "benign connective and soft tissue neoplasm of adipose tissue",
          "benign lipomatous neoplasm",
          "benign lipomatous tumor",
          "benign lipomatous tumour",
          "benign neoplasm of adipose tissue",
          "benign neoplasm of the adipose tissue",
          "benign tumor of the adipose tissue",
          "benign tumour of the adipose tissue",
          "benign tumor of adipose tissue",
          "benign tumour of adipose tissue"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign mesenchymal neoplasm composed of adipose (fatty) tissue. The most common representative of this category is the lipoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0044983"
    }
  ],
  "children": [
    {
      "id": 8023,
      "label": "diffuse lipomatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8054
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3923",
          "MEDGEN:272546",
          "NCIT:C6504",
          "UMLS:C1333298"
        ],
        "synonyms": [
          "diffuse lipomatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A neoplastic process characterized by a diffuse poorly circumscribed overgrowth of adipose tissue. It has been associated with several genetic disorders and different clinical conditions such as liver disease, excessive alcohol intake, adrenocortical steroid therapy, and antiretroviral therapy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006539"
    },
    {
      "id": 8057,
      "label": "mediastinal lipomatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8054
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3926",
          "EFO:1000732",
          "MEDGEN:233682",
          "NCIT:C27488",
          "UMLS:C1334662"
        ],
        "synonyms": [
          "mediastinal lipomatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A neoplastic process characterized by a diffuse poorly circumscribed overgrowth of adipose tissue in the mediastinum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006578"
    },
    {
      "id": 8069,
      "label": "pelvic lipomatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8054
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3927",
          "EFO:1000748",
          "MEDGEN:96064",
          "MESH:C535549",
          "NCIT:C27486",
          "UMLS:C0406608"
        ],
        "synonyms": [
          "pelvic lipomatosis",
          "pelvic lipomatosis (morphologic abnormality)",
          "Excess of mature unencapsulated fatty tissue in the pelvis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A neoplastic process characterized by a diffuse poorly circumscribed overgrowth of adipose tissue in the pelvic region. Clinical presentation includes complaints of back and abdominal pain, urinary frequency, perineal pain and constipation. It predominately affects black males."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006593"
    },
    {
      "id": 8087,
      "label": "steroid lipomatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8054
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3925",
          "MEDGEN:234364",
          "NCIT:C27487",
          "UMLS:C1336506"
        ],
        "synonyms": [
          "steroid lipomatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A neoplastic process characterized by a diffuse poorly circumscribed overgrowth of adipose tissue in the face, upper middle back, and sternal region. It is associated with adrenocortical steroid therapy or an increase in endogenous adrenocortical hormone."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006612"
    },
    {
      "id": 8485,
      "label": "adiposis dolorosa",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3052,
        8054,
        19144
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3928",
          "EFO:1000667",
          "GARD:0005750",
          "ICD9:272.8",
          "MEDGEN:1757",
          "MESH:D000274",
          "MedDRA:10001294",
          "NCIT:C84540",
          "NORD:1046",
          "OMIM:103200",
          "Orphanet:36397",
          "SCTID:71404003",
          "UMLS:C0001529",
          "Wikipedia:Adiposis_dolorosa"
        ],
        "synonyms": [
          "Adiposalgia",
          "Dercum disease",
          "Dercum's Disease",
          "Dercum's disease",
          "Neurolipomatosis",
          "adipose tissue rheumatism",
          "adiposis dolorosa",
          "lipomatosis dolorosa"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Adiposis dolorosa or Dercum's disease is characterized by the development of multiple, painful, subcutaneous lipomas in association with obesity, asthenia and fatigue, and range of mental disturbances including instability, depression, confusion, dementia and epilepsy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007070"
    },
    {
      "id": 9241,
      "label": "multiple symmetric lipomatosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3052,
        8054,
        19144,
        21247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14116",
          "EFO:1000737",
          "GARD:0006957",
          "MEDGEN:7349",
          "NCIT:C4392",
          "NORD:1392",
          "OMIM:151800",
          "Orphanet:2398",
          "SCTID:238902007",
          "UMLS:C0023804"
        ],
        "synonyms": [
          "Madelung disease",
          "Launois-Bensaude lipomatosis",
          "Madelung's Disease",
          "cephalothoracic lipodystrophy",
          "cervical symmetrical lipomatosis",
          "familial benign cervical lipomatosis",
          "lipodystrophy, cephalothoracic",
          "lipomatosis, familial benign cervical",
          "multiple symmetric lipomatosis",
          "multiple symmetrical lipomatosis",
          "Launois-Bensaude syndrome",
          "MSL",
          "Madelung's disease",
          "benign symmetrical lipomatosis",
          "familial symmetric lipomatosis",
          "lipomatosis, multiple symmetric"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A rare subcutaneous tissue disease characterized by growth of symmetric non-encapsulated masses of adipose tissue mostly around the face and neck with variable clinical repercussions (e.g. reduced neck mobility, compression of respiratory structures)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0007908"
    },
    {
      "id": 14112,
      "label": "encephalocraniocutaneous lipomatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8054,
        19144,
        20564,
        21247,
        23867
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002108",
          "ICD9:757.8",
          "MEDGEN:140807",
          "MESH:C535736",
          "NCIT:C4701",
          "OMIM:613001",
          "Orphanet:2396",
          "SCTID:238905009",
          "UMLS:C0406612",
          "icd11.foundation:1084215843"
        ],
        "synonyms": [
          "ECCL",
          "Fishman syndrome",
          "Haberland syndrome",
          "encephalocraniocutaneous lipomatosis",
          "encephalocraniocutaneous lipomatosis, somatic mosaic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A rare neoplastic syndrome characterized by the presence of unilateral lipomas of the cranium, face and neck, and ipsilateral cerebral malformations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013074"
    },
    {
      "id": 22871,
      "label": "congenital infiltrating lipomatosis of the face",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8054
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022333",
          "ICD10CM:Q87.3",
          "MEDGEN:1814459",
          "Orphanet:583097",
          "UMLS:C5680341",
          "icd11.foundation:1669603167"
        ],
        "synonyms": [
          "CIL-F",
          "facial infused lipomatosis",
          "fibroadipose infiltrating lipomatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035592"
    },
    {
      "id": 23148,
      "label": "pancreatic lipomatosis duodenal stenosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4734,
        8054,
        8191,
        20591
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:419702",
          "MESH:C535839",
          "UMLS:C2931040"
        ],
        "synonyms": [
          "pancreatic lipomatosis and duodenal atresia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0043166"
    }
  ],
  "roots": [
    {
      "id": 23492,
      "label": "benign lipomatous neoplasm"
    }
  ]
}