{
  "id": 8131,
  "label": "arthus reaction",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006660",
  "properties": {
    "xrefs": [
      "DOID:1556",
      "EFO:1000821",
      "ICD9:708.8",
      "ICD9:995.21",
      "MEDGEN:2458",
      "MESH:D001183",
      "MedDRA:10003420",
      "NCIT:C34400",
      "SCTID:402413008",
      "UMLS:C0003907"
    ],
    "synonyms": [
      "arthus phenomenon",
      "arthus reaction",
      "arthus reaction (function)"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "A localized vasculitis resulting from deposition of antibody-antigen complexes."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 8426,
      "label": "type III hypersensitivity disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3018,
        8586
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1557",
          "EFO:1001222",
          "MEDGEN:7021",
          "MESH:D007105",
          "MedDRA:10045265",
          "NCIT:C114346",
          "UMLS:C0020951"
        ],
        "synonyms": [
          "disorder of type III hypersensitivity",
          "type 3 hypersensitivity reaction",
          "type III hypersensitivity",
          "type III hypersensitivity reaction",
          "hypersensitivity reaction type III disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides serum sickness and the arthus reaction, evidence supports a pathogenic role for immune complexes in many other immune system diseases including glomerulonephritis, systemic lupus erythematosus (lupus erythematosus, systemic) and polyarteritis nodosa."
      },
      "child_count": 4,
      "reference_id": "MONDO:0007004"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 8426,
      "label": "type III hypersensitivity disease"
    }
  ]
}