{
  "id": 8139,
  "label": "bacterial meningitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006670",
  "properties": {
    "xrefs": [
      "DOID:9470",
      "EFO:1000831",
      "GARD:0005881",
      "ICD9:320",
      "ICD9:320.7",
      "ICD9:320.89",
      "ICD9:320.9",
      "MEDGEN:39048",
      "MESH:D016920",
      "MedDRA:10004049",
      "NCIT:C118297",
      "SCTID:95883001",
      "UMLS:C0085437",
      "icd11.foundation:684930313"
    ],
    "synonyms": [
      "Bacteria caused infectious meningitis",
      "Bacteria infectious meningitis",
      "meningitis, bacterial"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Inflammation of the membranes surrounding the brain and spinal cord due to a bacterial infection."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 6561,
      "label": "infectious meningitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20347,
        21534
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9471",
          "EFO:0000584",
          "GARD:0024106",
          "HP:0001287",
          "ICD9:321.8",
          "ICD9:322",
          "MEDGEN:152668",
          "NCIT:C79598",
          "SCTID:312216007",
          "UMLS:C0729584"
        ],
        "synonyms": [
          "infectious meningitis",
          "infective meningitis",
          "meningitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Inflammation of the meninges of the brain and/or spinal cord caused by an infectious agent (viral, bacterial, or fungal). Symptoms include headache, fever, vomiting, neck stiffness, photophobia, confusion, and seizures."
      },
      "child_count": 10,
      "reference_id": "MONDO:0004796"
    },
    {
      "id": 6839,
      "label": "bacterial infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7200
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:104",
          "EFO:0000771",
          "ICD9:040.89",
          "ICD9:041.89",
          "ICD9:041.9",
          "MEDGEN:14012",
          "MESH:D001424",
          "NCIT:C2890",
          "SCTID:87628006",
          "UMLS:C0004623"
        ],
        "synonyms": [
          "Bacteria caused disease or disorder",
          "Bacteria disease or disorder",
          "Bacteria infectious disease",
          "bacterial disease",
          "bacterial disorder",
          "bacterial infection",
          "bacterial infectious disease",
          "infection, bacterial",
          "infections, bacterial"
        ],
        "definition": "An acute infectious disorder that is caused by gram positive or gram negative bacteria; representative examples include pneumococcal, streptococcal, salmonella, and meningeal infections."
      },
      "child_count": 52,
      "reference_id": "MONDO:0005113"
    }
  ],
  "children": [
    {
      "id": 3169,
      "label": "haemophilus meningitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8139,
        8359
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080179",
          "EFO:1000955",
          "GARD:0022838",
          "ICD9:320.0",
          "MEDGEN:7535",
          "MESH:D008583",
          "MedDRA:10018953",
          "SCTID:192643004",
          "SCTID:5900006",
          "UMLS:C0025292"
        ],
        "synonyms": [
          "Haemophilus influenzae bacterial meningitis",
          "Haemophilus influenzae caused bacterial meningitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Infections of the nervous system caused by bacteria of the genus haemophilus, and marked by prominent inflammation of the meninges. haemophilus influenzae type B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000889"
    },
    {
      "id": 3547,
      "label": "streptococcal meningitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8139,
        20725
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11574",
          "GARD:0022920",
          "ICD10CM:G00.2",
          "ICD9:320.2",
          "MEDGEN:509616",
          "SCTID:4510004",
          "UMLS:C0154639",
          "icd11.foundation:705971711"
        ],
        "synonyms": [
          "Streptococcus caused infectious meningitis",
          "Streptococcus infectious meningitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An infectious meningitis caused by infection with Streptococcus."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001316"
    },
    {
      "id": 4159,
      "label": "anaerobic meningitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8139,
        21395
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14559",
          "GARD:0023056",
          "ICD9:320.81",
          "MEDGEN:678523",
          "SCTID:445059005",
          "UMLS:C0854214"
        ],
        "synonyms": [
          "meningitis caused by anaerobic bacteria",
          "meningitis due to anaerobic bacteria"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0002000"
    },
    {
      "id": 7628,
      "label": "meningeal tuberculosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2810,
        7327,
        8139
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000039",
          "GARD:0007828",
          "ICD10CM:A17.0",
          "MEDGEN:21725",
          "MESH:D014390",
          "NCIT:C84888",
          "NORD:1437",
          "Orphanet:499004",
          "SCTID:58437007",
          "UMLS:C0041318"
        ],
        "synonyms": [
          "Meningitis, Tuberculous",
          "TB meningitis",
          "TBM",
          "tubercular meningitis",
          "tuberculous meningitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A bacterial infection of the membranes covering the brain and the spinal cord caused by Mycobacterium tuberculosis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006042"
    },
    {
      "id": 8208,
      "label": "Escherichia coli meningitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8139
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000929",
          "GARD:0024466",
          "ICD9:320.7",
          "ICD9:320.82",
          "MEDGEN:90920",
          "MESH:D020814",
          "SCTID:192655005",
          "UMLS:C0338395"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A form of gram-negative meningitis that tends to occur in neonates, in association with anatomical abnormalities (which feature communication between the meninges and cutaneous structures) or as opportunistic infections in association with immunologic deficiency syndromes. In premature neonates the clinical presentation may be limited to anorexia; vomiting; lethargy; or respiratory distress. Full-term infants may have as additional features fever; seizures; and bulging of the anterior fontanelle. (From Menkes, Textbook of Child Neurology, 5th ed, pp398-400)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0006753"
    },
    {
      "id": 8280,
      "label": "Listeria meningitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7442,
        8139
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11572",
          "EFO:1001021",
          "GARD:0024482",
          "ICD9:320.7",
          "MEDGEN:7536",
          "MESH:D008584",
          "SCTID:31568009",
          "UMLS:C0025293"
        ],
        "synonyms": [
          "Listeria meningitis",
          "Listeria monocytogenes caused infectious meningitis",
          "Listeria monocytogenes infectious meningitis",
          "Cerebritides, Listeria",
          "Listeria Cerebritides",
          "Listeria Meningitides",
          "Listeria Meningoencephalitides",
          "Listeria cerebritis",
          "Listeria meningoencephalitis",
          "Listeria monocytogenes Meningitides",
          "Listeria monocytogenes meningitis",
          "Meningitides, Listeria",
          "Meningitides, Listeria monocytogenes",
          "Meningoencephalitides, Listeria",
          "cerebritis, Listeria",
          "meningitis, Listeria monocytogenes",
          "meningoencephalitis, Listeria"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Inflammation of the meninges caused by listeria monocytogenes infection, usually occurring in individuals under the age of 3 years or over the age of 50 years. It may occur at any age in individuals with immunologic deficiency syndromes. Clinical manifestations include fever, altered mentation, headache, meningeal signs, focal neurologic signs, and seizures. (From Medicine 1998 Sep;77(5):313-36)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0006836"
    },
    {
      "id": 18222,
      "label": "meningococcal meningitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7054,
        8139
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080176",
          "EFO:1001040",
          "GARD:0018809",
          "ICD10CM:A39.0",
          "ICD9:036.0",
          "MEDGEN:6299",
          "MESH:D008585",
          "MedDRA:10027249",
          "MedDRA:10027276",
          "NORD:1438",
          "Orphanet:33475",
          "SCTID:192644005",
          "UMLS:C0025294",
          "icd11.foundation:516585689"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An acute bacterial disease caused by Neisseria meningitides that presents usually, but not always, with a rash (non blanching petechial or purpuric rash), progressively developing signs of meningitis (fever, vomiting, headache, photophobia, and neck stiffness) and later leading to confusion, delirium and drowsiness. Neck stiffness and photophobia are often absent in infants and young children who may manifest nonspecific signs such as irritability, inconsolable crying, poor feeding, and a bulging fontanel. Meningococcal meningitis may also present as part of early or late onset sepsis in neonates. The disease is potentially fatal. Surviving patients may develop neurological sequelae that include sensorineural hearing loss, seizures, spasticity, attention deficits and intellectual disability."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018059"
    },
    {
      "id": 23046,
      "label": "bacterial meningitis caused by gram-negative bacteria",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8139,
        20723
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025842",
          "MEDGEN:678524",
          "SCTID:425887005",
          "UMLS:C0854215"
        ],
        "synonyms": [
          "bacterial meningitis caused by gram-negative bacteria",
          "bacterial meningitis due to gram-negative bacteria",
          "gram-negative bacterial meningitis",
          "meningitis with gram negative bacteria",
          "meningitis with gramme negative bacteria"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0041825"
    }
  ],
  "roots": [
    {
      "id": 6561,
      "label": "infectious meningitis"
    },
    {
      "id": 6839,
      "label": "bacterial infectious disease"
    }
  ]
}