{
  "id": 8158,
  "label": "cerebral arterial disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006693",
  "properties": {
    "xrefs": [
      "DOID:3527",
      "EFO:1000859",
      "MEDGEN:2963",
      "MESH:D002539",
      "UMLS:C0007774"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Pathological conditions of intracranial arteries supplying the cerebrum. These diseases often are due to abnormalities or pathological processes in the anterior cerebral artery; middle cerebral artery; and posterior cerebral artery."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 8256,
      "label": "intracranial arterial disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        12183
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13089",
          "EFO:1000990",
          "MEDGEN:199819",
          "MESH:D020765",
          "UMLS:C0752138"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Pathological conditions involving arteries in the skull, such as arteries supplying the cerebrum, the cerebellum, the brain stem, and associated structures. They include atherosclerotic, congenital, traumatic, infectious, inflammatory, and other pathological processes."
      },
      "child_count": 1,
      "reference_id": "MONDO:0006808"
    }
  ],
  "children": [
    {
      "id": 6985,
      "label": "brain aneurysm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8158
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10941",
          "EFO:0003870",
          "MEDGEN:196706",
          "MESH:D002532",
          "UMLS:C0751003"
        ],
        "synonyms": [
          "intracranial aneurysm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A congenital or acquired aneurysm within the cranium."
      },
      "child_count": 1,
      "reference_id": "MONDO:0005291"
    },
    {
      "id": 8300,
      "label": "middle cerebral artery infarction",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4726,
        8158
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3525",
          "EFO:1001045",
          "MEDGEN:152845",
          "MESH:D020244",
          "UMLS:C0740392"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Necrosis occurring in the middle cerebral artery distribution system which brings blood to the entire lateral aspects of each cerebral hemisphere. Clinical signs include impaired cognition; aphasia; agraphia; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006857"
    },
    {
      "id": 8350,
      "label": "posterior cerebral artery infarction",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4726,
        8158
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3821",
          "EFO:1001118",
          "MEDGEN:199818",
          "MESH:D020762",
          "UMLS:C0752132"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Necrosis induced by ischemia in the posterior cerebral artery distribution system which supplies portions of the brain stem; the thalamus; temporal lobe, and occipital lobe. Depending on the size and location of infarction, clinical features include olfaction disorders and visual problems (agnosia; alexia; hemianopsia)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006917"
    },
    {
      "id": 17246,
      "label": "Moyamoya disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8158,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13099",
          "GARD:0007064",
          "ICD10CM:I67.5",
          "MEDGEN:7726",
          "MESH:D009072",
          "MedDRA:10028047",
          "NANDO:1200183",
          "NANDO:2100228",
          "NANDO:2200850",
          "NCIT:C84895",
          "NORD:1457",
          "OMIMPS:252350",
          "Orphanet:2573",
          "SCTID:89142007",
          "UMLS:C0026654",
          "icd11.foundation:1746892088",
          "icd11.foundation:369231682"
        ],
        "synonyms": [
          "idiopathic Moyamoya disease",
          "progressive intracranial arterial occlusion",
          "MYMY",
          "Moyamoya disease, primary",
          "Moyamoya disease, secondary"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Moyamoya disease (MMD) is a rare intracranial arteriopathy involving progressive stenosis of the cerebral vasculature located at the base of the brain causing transient ischemic attacks or strokes."
      },
      "child_count": 16,
      "reference_id": "MONDO:0016820"
    }
  ],
  "roots": [
    {
      "id": 8256,
      "label": "intracranial arterial disease"
    }
  ]
}