{
  "id": 8165,
  "label": "chronic inflammatory demyelinating polyradiculoneuropathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006702",
  "properties": {
    "xrefs": [
      "DOID:5213",
      "EFO:1000868",
      "GARD:0006102",
      "ICD10CM:G61.81",
      "ICD9:357.81",
      "ICD9:357.89",
      "MEDGEN:98292",
      "MESH:D020277",
      "MedDRA:10057645",
      "NANDO:1200030",
      "NANDO:2100251",
      "NANDO:2200905",
      "NCIT:C84636",
      "Orphanet:2932",
      "SCTID:128209004",
      "UMLS:C0393819",
      "icd11.foundation:224318510"
    ],
    "synonyms": [
      "CIDP",
      "chronic inflammatory demyelinating polyneuropathy",
      "chronic inflammatory demyelinating polyradiculoneuropathy",
      "chronic relapsing polyneuropathy",
      "chronic inflammatory demyelinating polyneuritis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A rare neurological disorder in which there is inflammation of nerve roots and peripheral nerves and destruction of the fatty protective covering (myelin sheath) over the nerves. This affects how fast the nerve signals are transmitted and leads to loss of nerve fibers. This causes weakness, paralysis and/or impairment in motor function, especially of the arms and legs (limbs). Sensory disturbance may also be present. The motor and sensory impairments usually affect both sides of the body (symmetrical), and the degree of severity and the course of disease may vary from case to case. Some affected individuals may follow a slow steady pattern of symptoms while others may have symptoms that stabilize and then relapse."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5272,
      "label": "demyelinating polyneuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4005,
        4626
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5214",
          "GARD:0023456",
          "ICD9:356.9",
          "MEDGEN:82859",
          "NCIT:C27062",
          "SCTID:23414001",
          "UMLS:C0270922"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Polyneuropathy that is characterized by demyelination of axons."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003334"
    },
    {
      "id": 5273,
      "label": "chronic polyneuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5221",
          "MEDGEN:223911",
          "NCIT:C36071",
          "UMLS:C1167650"
        ],
        "synonyms": [
          "polyneuropathy, chronic"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Polyneuropathy that is persistent or long-standing in nature."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003335"
    },
    {
      "id": 8348,
      "label": "polyradiculoneuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4005,
        4626
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4308",
          "EFO:1001116",
          "GARD:0024500",
          "MEDGEN:46012",
          "MESH:D011129",
          "SCTID:128078004",
          "UMLS:C0032587"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (guillain-barre syndrome) and polyradiculoneuropathy, chronic inflammatory demyelinating. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006915"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 18766,
      "label": "Lewis-Sumner syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0013070",
          "MEDGEN:798498",
          "MedDRA:10065580",
          "Orphanet:48162",
          "UMLS:C1695985"
        ],
        "synonyms": [
          "MADSAM",
          "multifocal acquired demyelinating sensory and motor neuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare acquired demyelinating polyneuropathy characterized by asymmetrical distal weakness of the upper or lower extremities and motor dysfunction with adult onset. It is considered to be a variant of chronic inflammatory demyelinating polyneuropathy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018826"
    }
  ],
  "roots": [
    {
      "id": 5272,
      "label": "demyelinating polyneuropathy"
    },
    {
      "id": 5273,
      "label": "chronic polyneuropathy"
    },
    {
      "id": 8348,
      "label": "polyradiculoneuropathy"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}