{
  "id": 8316,
  "label": "oophoritis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006877",
  "properties": {
    "xrefs": [
      "DOID:10974",
      "EFO:1001071",
      "MEDGEN:14486",
      "MESH:D009869",
      "MedDRA:10030345",
      "SCTID:76047005",
      "UMLS:C0029051"
    ],
    "synonyms": [
      "inflammation of ovary",
      "ovary inflammation"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Inflammation of the ovary, generally caused by an ascending infection of organisms from the endocervix."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7207,
      "label": "ovarian disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4375,
        4379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1100",
          "EFO:0005771",
          "MEDGEN:892314",
          "MESH:D010049",
          "NCIT:C26841",
          "SCTID:5552004",
          "UMLS:C4021818"
        ],
        "synonyms": [
          "disease of ovary",
          "disease or disorder of ovary",
          "disorder of ovary",
          "ovarian disease",
          "ovarian disorder",
          "ovary disease",
          "ovary disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A disease involving the ovary."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005558"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 3416,
      "label": "salpingo-oophoritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5511,
        8316
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10972",
          "ICD9:614.2",
          "MEDGEN:508106",
          "NCIT:C171201",
          "SCTID:46536000",
          "UMLS:C0036133"
        ],
        "synonyms": [
          "Tubo-ovarian inflammatory disease",
          "tubo ovarian abscess",
          "tubo-ovarian abscess",
          "tubo-ovarian abscess (disorder)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 4,
      "reference_id": "MONDO:0001172"
    },
    {
      "id": 4345,
      "label": "tuberculous oophoritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7593,
        8316
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2148",
          "GARD:0023092",
          "ICD9:016.6",
          "ICD9:016.60",
          "MEDGEN:546959",
          "SCTID:84194006",
          "UMLS:C0275932",
          "icd11.foundation:1634640694"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An urogenital tuberculosis involving a pathogenic inflammatory response in the ovary."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002226"
    },
    {
      "id": 20790,
      "label": "autoimmune oophoritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2997,
        8316
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:163900",
          "MESH:C538274",
          "UMLS:C0878654"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Autoimmune oophoritis is a rare cause of primary ovarian insufficiency (POI). It happens when the body's immune system mistakenly attacks the ovaries causing inflammation, atrophy and fibrosis. These changes stop the ovaries from working normally. The main symptoms of autoimmune oophorotis are irregular or absent menstrual period (amenorrhea) and symptoms related to ovarian cysts such as abdominal cramping, bloating, nausea and vomiting. Autoimmune oophoritis may occur as part of autoimmune polyglandular syndrome type I and type II but has also been associated with lupus, pernicious anemia, myasthenia gravis and other autoimmune conditions. The underlying cause of autoimmune oophoritis is unknown. Diagnosis involves a special blood test which looks for anti-steroid or anti-ovarian antibodies, a pelvic ultrasound to look for enlarged cystic ovaries and tests to rule out other possible causes of POI. Management of autoimmune oophoritis involves emotional support, possible estrogen replacement therapy and management of other autoimmune conditions."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021950"
    }
  ],
  "roots": [
    {
      "id": 7207,
      "label": "ovarian disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}