{
  "id": 8324,
  "label": "thyroid gland papillary and follicular carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006886",
  "properties": {
    "xrefs": [
      "DOID:3968",
      "EFO:1001083",
      "GARD:0024498",
      "MEDGEN:64631",
      "MESH:D018265",
      "NCIT:C7380",
      "UMLS:C0206683"
    ],
    "synonyms": [
      "papillary and follicular adenocarcinoma",
      "papillary and follicular carcinoma",
      "thyroid gland papillary and follicular carcinoma",
      "papillary follicular thyroid adenocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A thyroid neoplasm of mixed papillary and follicular arrangement. Its biological behavior and prognosis is the same as that of a papillary adenocarcinoma of the thyroid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1271)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6768,
      "label": "thyroid gland follicular carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16290,
        21537
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3962",
          "EFO:0000501",
          "GARD:0024144",
          "HP:0006731",
          "ICDO:8330/3",
          "ICDO:8331/3",
          "MEDGEN:64630",
          "MESH:D018263",
          "NCIT:C8054",
          "ONCOTREE:THFO",
          "SCTID:255028004",
          "UMLS:C0206682"
        ],
        "synonyms": [
          "follicular cancer of the thyroid",
          "follicular cancer of the thyroid gland",
          "follicular cancer of thyroid",
          "follicular cancer of thyroid gland",
          "thyroid gland follicular cancer",
          "well-differentiated follicular carcinoma",
          "carcinoma of thyroid follicle",
          "carcinoma, follicular cell, malignant",
          "follicular carcinoma",
          "follicular carcinoma of the thyroid",
          "follicular carcinoma of the thyroid gland",
          "follicular carcinoma of thyroid",
          "follicular carcinoma of thyroid gland",
          "follicular thyroid cancer",
          "follicular thyroid carcinoma",
          "follicular thyroid gland carcinoma",
          "thyroid follicle carcinoma",
          "thyroid follicular carcinoma",
          "thyroid gland follicular carcinoma",
          "well-differentiated follicular adenocarcinoma",
          "follicular adenocarcinoma",
          "follicular adenocarcinoma (morphologic abnormality)",
          "follicular adenocarcinoma, well differentiated",
          "follicular adenocarcinoma, well differentiated (morphologic abnormality)",
          "thyroid gland adenocarcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. The nuclear features which characterize the thyroid gland papillary carcinoma are absent. Radiation exposure is a risk factor and it comprises approximately 10% to 15% of thyroid cancers. Clinically, it usually presents as a solitary mass in the thyroid gland. It is generally unifocal and thickly encapsulated and shows invasion of the capsule or the vessels. Diagnostic procedures include thyroid ultrasound and fine needle biopsy."
      },
      "child_count": 14,
      "reference_id": "MONDO:0005034"
    },
    {
      "id": 6803,
      "label": "thyroid gland papillary carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4583,
        16290,
        21537
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3969",
          "EFO:0000641",
          "GARD:0024148",
          "HP:0002895",
          "MEDGEN:66773",
          "NCIT:C4035",
          "ONCOTREE:THPA",
          "SCTID:255029007",
          "UMLS:C0238463"
        ],
        "synonyms": [
          "papillary cancer of the thyroid",
          "papillary cancer of the thyroid gland",
          "papillary cancer of thyroid",
          "papillary cancer of thyroid gland",
          "papillary carcinoma of the thyroid",
          "papillary carcinoma of the thyroid gland",
          "papillary carcinoma of thyroid",
          "papillary carcinoma of thyroid gland",
          "papillary thyroid cancer",
          "papillary thyroid carcinoma",
          "papillary thyroid gland carcinoma",
          "thyroid gland papillary cancer",
          "thyroid gland papillary carcinoma",
          "thyroid papillary carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. Radiation exposure is a risk factor and it is the most common malignant thyroid lesion, comprising 75% to 80% of all thyroid cancers in iodine sufficient countries. Diagnostic procedures include thyroid ultrasound and fine needle biopsy. Microscopically, the diagnosis is based on the distinct characteristics of the malignant cells, which include enlargement, oval shape, elongation, and overlapping of the nuclei. The nuclei also display clearing or have a ground glass appearance."
      },
      "child_count": 18,
      "reference_id": "MONDO:0005075"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6768,
      "label": "thyroid gland follicular carcinoma"
    },
    {
      "id": 6803,
      "label": "thyroid gland papillary carcinoma"
    }
  ]
}