{
  "id": 8328,
  "label": "parathyroid gland adenoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006890",
  "properties": {
    "xrefs": [
      "DOID:7608",
      "EFO:1001087",
      "HP:0002897",
      "MEDGEN:75502",
      "MedDRA:10033940",
      "NCIT:C156757",
      "NCIT:C3916",
      "SCTID:128474007",
      "UMLS:C0262587"
    ],
    "synonyms": [
      "adenoma of parathyroid",
      "adenoma of parathyroid gland",
      "adenoma of the parathyroid",
      "parathyroid adenoma",
      "parathyroid gland adenoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A benign tumor arising from the parenchymal cells of the parathyroid glands. In the vast majority of cases, the tumor involves a single parathyroid gland. It is associated with the symptoms of primary hyperparathyroidism, resulting from the excessive production of parathyroid hormone. It is usually surrounded by a well-defined capsule. Capsular invasion, vascular invasion, and perineural invasion are absent."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 6714,
      "label": "adenoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:657",
          "EFO:0000232",
          "ICDO:8140/0",
          "MEDGEN:125",
          "MESH:D000236",
          "NCIT:C2855",
          "SCTID:443416007",
          "UMLS:C0001430"
        ],
        "synonyms": [
          "adenoma",
          "acinar cell adenoma",
          "acinar cell adenoma (morphologic abnormality)",
          "adenoma, benign"
        ],
        "definition": "A neoplasm arising from the epithelium. It may be encapsulated or non-encapsulated but non-invasive. The neoplastic epithelial cells may or may not display cellular atypia or dysplasia. In the gastrointestinal tract, when dysplasia becomes severe it is sometimes called carcinoma in situ. Representative examples are pituitary gland adenoma, follicular adenoma of the thyroid gland, and adenomas (or adenomatous polyps) of the gastrointestinal tract."
      },
      "child_count": 31,
      "reference_id": "MONDO:0004972"
    },
    {
      "id": 20585,
      "label": "benign neoplasm of parathyroid gland",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3032,
        20525
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:60008",
          "ICD10CM:D35.1",
          "ICD9:227.1",
          "MEDGEN:57814",
          "NCIT:C3630",
          "SCTID:92272009",
          "UMLS:C0154041",
          "icd11.foundation:455097662"
        ],
        "synonyms": [
          "benign neoplasm of parathyroid",
          "benign neoplasm of the parathyroid",
          "benign neoplasm of the parathyroid gland",
          "benign parathyroid gland neoplasm",
          "benign parathyroid gland tumor",
          "benign parathyroid gland tumour",
          "benign parathyroid neoplasm",
          "benign parathyroid tumor",
          "benign parathyroid tumour",
          "benign tumor of parathyroid",
          "benign tumor of parathyroid gland",
          "benign tumor of the parathyroid",
          "benign tumor of the parathyroid gland",
          "benign tumour of parathyroid",
          "benign tumour of parathyroid gland",
          "benign tumour of the parathyroid",
          "benign tumour of the parathyroid gland",
          "parathyroid gland benign neoplasm",
          "parathyroid tumor benign",
          "parathyroid tumour benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the parathyroid gland."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021463"
    },
    {
      "id": 22952,
      "label": "benign epithelial neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6887,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICDO:8010/0",
          "ICDO:8011/0",
          "MEDGEN:90747",
          "NCIT:C4092",
          "UMLS:C0334232"
        ],
        "synonyms": [
          "benign epithelial neoplasm",
          "benign epithelial tumor",
          "benign epithelial tumour",
          "benign epithelioma",
          "benign neoplasm of epithelium",
          "benign neoplasm of the epithelium",
          "benign tumor of epithelium",
          "benign tumor of the epithelium",
          "benign tumour of epithelium",
          "benign tumour of the epithelium",
          "epithelial neoplasm, benign",
          "epithelioma, benign"
        ],
        "definition": "A neoplasm arising from the epithelial cells. It is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign epithelial neoplasms remain confined to the original site of growth and only rarely metastasize to other anatomic sites."
      },
      "child_count": 50,
      "reference_id": "MONDO:0036976"
    }
  ],
  "children": [
    {
      "id": 6118,
      "label": "chief cell adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7607",
          "ICDO:8321/0",
          "MEDGEN:83128",
          "NCIT:C4154",
          "UMLS:C0334320"
        ],
        "synonyms": [
          "chief cell adenoma",
          "chief cell adenoma of parathyroid",
          "chief cell adenoma of parathyroid gland",
          "chief cell adenoma of the parathyroid",
          "chief cell adenoma of the parathyroid gland",
          "parathyroid chief cell adenoma",
          "parathyroid gland chief cell adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A parathyroid gland adenoma composed predominantly of neoplastic chief cells. These cells have either slightly eosinophilic or vacuolated cytoplasm, and round nuclei."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004302"
    },
    {
      "id": 6119,
      "label": "parathyroid gland clear cell adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5354,
        8328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7609",
          "MEDGEN:83546",
          "NCIT:C7993",
          "UMLS:C0279700"
        ],
        "synonyms": [
          "clear cell adenoma of parathyroid",
          "clear cell adenoma of parathyroid gland",
          "clear cell adenoma of the parathyroid",
          "clear cell adenoma of the parathyroid gland",
          "parathyroid clear cell adenoma",
          "parathyroid gland clear cell adenoma",
          "parathyroid gland transitional clear cell adenoma",
          "parathyroid transitional clear cell adenoma",
          "transitional clear cell adenoma of parathyroid",
          "transitional clear cell adenoma of parathyroid gland",
          "transitional clear cell adenoma of the parathyroid",
          "transitional clear cell adenoma of the parathyroid gland"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A parathyroid gland adenoma composed predominantly of neoplastic cells with clear cytoplasm."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004303"
    },
    {
      "id": 6120,
      "label": "mixed cell type adenoma of parathyroid",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5349,
        8328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7610",
          "MEDGEN:83547",
          "NCIT:C7994",
          "UMLS:C0279701"
        ],
        "synonyms": [
          "mixed cell type adenoma of parathyroid",
          "mixed cell type adenoma of parathyroid gland",
          "mixed cell type adenoma of the parathyroid",
          "mixed cell type adenoma of the parathyroid gland",
          "parathyroid gland mixed cell type adenoma",
          "parathyroid mixed cell type adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A parathyroid gland adenoma that contains a mixture of neoplastic cells (chief cells, oncocytes, and clear cells)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004304"
    },
    {
      "id": 6121,
      "label": "parathyroid oncocytic adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5352,
        8328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7611",
          "MEDGEN:233845",
          "NCIT:C27393",
          "UMLS:C1335351"
        ],
        "synonyms": [
          "parathyroid gland oncocytic adenoma",
          "parathyroid oncocytic adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A parathyroid gland adenoma composed predominantly or entirely of neoplastic cells with abundant granular eosinophilic cytoplasm."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004305"
    },
    {
      "id": 19971,
      "label": "familial parathyroid adenoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5714,
        8328
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:374460",
          "Orphanet:99877",
          "UMLS:C1840403",
          "icd11.foundation:55934726"
        ],
        "synonyms": [
          "hereditary parathyroid gland adenoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An instance of parathyroid gland adenoma that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020523"
    }
  ],
  "roots": [
    {
      "id": 6714,
      "label": "adenoma"
    },
    {
      "id": 20585,
      "label": "benign neoplasm of parathyroid gland"
    },
    {
      "id": 22952,
      "label": "benign epithelial neoplasm"
    }
  ]
}