{
  "id": 8383,
  "label": "rheumatic heart disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006955",
  "properties": {
    "xrefs": [
      "DOID:0050827",
      "EFO:1001161",
      "ICD9:398.90",
      "ICD9:398.99",
      "MEDGEN:20565",
      "MESH:D012214",
      "MedDRA:10062110",
      "NCIT:C34882",
      "SCTID:23685000",
      "UMLS:C0035439",
      "icd11.foundation:291726710"
    ],
    "synonyms": [
      "RHD",
      "disease, rheumatic heart",
      "heart disease, rheumatic",
      "rheumatic carditis"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "An autoinflammatory condition following an infection with Group A Beta Hemolytic Streptococcus (GABHS), in which the heart is attacked by antibodies formed in reaction to a recent GABHS infection. Chief anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords, all of which can result in valvular dysfunction."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6967,
      "label": "heart disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:114",
          "EFO:0003777",
          "ICD9:429.89",
          "ICD9:429.9",
          "ICD9:V47.2",
          "MEDGEN:5458",
          "MESH:D006331",
          "NCIT:C3079",
          "SCTID:56265001",
          "UMLS:C0018799",
          "icd11.foundation:1512587470"
        ],
        "synonyms": [
          "cardiac disease",
          "disease of heart",
          "disease or disorder of heart",
          "disorder of heart",
          "disorder of heart/pericardium",
          "heart disease",
          "heart disease or disorder",
          "heart disorder",
          "heart trouble",
          "heart/pericardial disease",
          "heart/pericardial disease or disorder",
          "heart/pericardial disorder",
          "heart/pericardial trouble"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disease involving the heart and/or pericardium."
      },
      "child_count": 34,
      "reference_id": "MONDO:0005267"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 4073,
      "label": "rheumatic congestive heart failure",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6747,
        8383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14172",
          "ICD10CM:I09.81",
          "ICD9:398.91",
          "MEDGEN:510028",
          "SCTID:82523003",
          "UMLS:C0155582"
        ],
        "synonyms": [
          "rheumatic heart failure",
          "rheumatic heart failure (congestive)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001899"
    },
    {
      "id": 6378,
      "label": "rheumatic myocarditis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6298,
        8383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8481",
          "GARD:0024072",
          "ICD10CM:I09.0",
          "ICD9:391.9",
          "ICD9:398.0",
          "MEDGEN:56370",
          "NCIT:C35202",
          "SCTID:195136004",
          "UMLS:C0155557",
          "icd11.foundation:1177212968"
        ],
        "synonyms": [
          "acute rheumatic myocarditis",
          "acute rheumatic myocarditis (disorder) [ambiguous]",
          "rheumatic myocarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Inflammation of the myocardium in acute rheumatic heart disease."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004582"
    },
    {
      "id": 20751,
      "label": "acute rheumatic heart disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8383,
        20092
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:391.8",
          "ICD9:391.9",
          "MEDGEN:19779",
          "NCIT:C34985",
          "SCTID:312591002",
          "UMLS:C0035440",
          "icd11.foundation:535094176"
        ],
        "synonyms": [
          "acute rheumatic heart disease",
          "Active rheumatic fever with heart involvement",
          "active rheumatic fever with heart involvement",
          "acute Rheumatic Heart Disease",
          "acute rheumatic carditis",
          "acute rheumatic fever with heart involvement"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Pancarditis, involving inflammation of the endocardium, myocardium, and epicardium. It results from an autoimmune reaction following an infection with Streptococcus pyogenes (Group A Streptococci)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021777"
    },
    {
      "id": 21563,
      "label": "rheumatic pericarditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7506,
        8383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:538808",
          "SCTID:28381002",
          "UMLS:C0264747"
        ],
        "synonyms": [
          "rheumatic pericarditis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0024655"
    }
  ],
  "roots": [
    {
      "id": 6967,
      "label": "heart disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}