{
  "id": 8422,
  "label": "tooth disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0006999",
  "properties": {
    "xrefs": [
      "DOID:1091",
      "EFO:1001216",
      "MEDGEN:11852",
      "MESH:D014076",
      "NCIT:C35077",
      "SCTID:234947003",
      "UMLS:C0040435"
    ],
    "synonyms": [
      "calcareous tooth disease",
      "calcareous tooth disease or disorder",
      "dental disorder",
      "disease of calcareous tooth",
      "disease or disorder of calcareous tooth",
      "disorder of calcareous tooth",
      "tooth disorder"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      }
    ],
    "definition": "A disease involving the calcareous tooth."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 11,
  "parents": [
    {
      "id": 6893,
      "label": "skeletal system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0002461",
          "MEDGEN:538042",
          "SCTID:88230002",
          "UMLS:C0263661"
        ],
        "synonyms": [
          "disease of skeletal system",
          "disease or disorder of skeletal system",
          "disorder of skeletal system",
          "skeletal system disease",
          "skeletal system disease or disorder",
          "disease of bone and/or joint",
          "osteoarthropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A disease involving the skeletal system."
      },
      "child_count": 48,
      "reference_id": "MONDO:0005172"
    },
    {
      "id": 8301,
      "label": "mouth disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:403",
          "EFO:1001047",
          "ICD9:528.9",
          "MEDGEN:6448",
          "MESH:D009059",
          "NCIT:C3240",
          "SCTID:118938008",
          "UMLS:C0026636"
        ],
        "synonyms": [
          "disease of mouth",
          "disease or disorder of mouth",
          "disorder of mouth",
          "mouth disease",
          "mouth disease or disorder",
          "oral disease",
          "oral disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A disease involving the mouth."
      },
      "child_count": 27,
      "reference_id": "MONDO:0006858"
    }
  ],
  "children": [
    {
      "id": 3121,
      "label": "dental abscess",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060324",
          "MEDGEN:99235",
          "SCTID:299709002",
          "UMLS:C0518988"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A tooth disease characterized by a localized collection of pus associated with a tooth."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000750"
    },
    {
      "id": 4339,
      "label": "tooth hard tissue disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:214",
          "ICD10CM:K03",
          "ICD9:521.8",
          "ICD9:521.89",
          "MEDGEN:510140",
          "SCTID:46557008",
          "UMLS:C0155926"
        ],
        "synonyms": [
          "disorder of hard tissues of teeth",
          "teeth hard tissue disease",
          "teeth hard tissue diseases"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ]
      },
      "child_count": 7,
      "reference_id": "MONDO:0002220"
    },
    {
      "id": 4431,
      "label": "tooth erosion, non-bacterial",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2498",
          "ICD9:521.3",
          "ICD9:521.30",
          "ICD9:521.34",
          "ICD9:521.35",
          "MEDGEN:21584",
          "MESH:D014077",
          "SCTID:82212003",
          "UMLS:C0040436"
        ],
        "synonyms": [
          "generalised erosion",
          "generalized erosion",
          "localised erosion",
          "localized erosion"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "Progressive loss of tooth tissue by chemical processes that do not involve bacterial action. (Jablonski, Dictionary of Dentistry, 1992, p296)"
      },
      "child_count": 2,
      "reference_id": "MONDO:0002325"
    },
    {
      "id": 5326,
      "label": "dental pulp disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5330",
          "EFO:0009540",
          "ICD9:522.9",
          "MEDGEN:8305",
          "MESH:D003788",
          "NCIT:C34530",
          "SCTID:57203004",
          "UMLS:C0011405"
        ],
        "synonyms": [
          "dental pulp disease",
          "dental pulp disease or disorder",
          "dental pulp disorder",
          "disease of dental pulp",
          "disease or disorder of dental pulp",
          "disorder of dental pulp"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A disease involving the dental pulp."
      },
      "child_count": 7,
      "reference_id": "MONDO:0003394"
    },
    {
      "id": 7142,
      "label": "tooth agenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050591",
          "EFO:0005410",
          "ICD10CM:K00.0",
          "ICD9:520.0",
          "MEDGEN:43794",
          "OMIMPS:106600",
          "Orphanet:2227",
          "Orphanet:99798",
          "SCTID:64969001",
          "UMLS:C0020608",
          "icd11.foundation:1559717619"
        ],
        "synonyms": [
          "hypodontia",
          "selective tooth agenesis",
          "tooth agenesis, selective",
          "oligodontia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A tooth disease characterized by failure to develop one or more missing teeth."
      },
      "child_count": 24,
      "reference_id": "MONDO:0005486"
    },
    {
      "id": 8182,
      "label": "dental fluorosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13711",
          "EFO:1000892",
          "ICD10CM:K00.3",
          "ICD9:520.3",
          "MEDGEN:44506",
          "MESH:D009050",
          "MedDRA:10016819",
          "NCIT:C85059",
          "SCTID:30265004",
          "UMLS:C0026618"
        ],
        "synonyms": [
          "fluorosis",
          "mottled teeth",
          "mottling of enamel"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A condition that results from excessive fluoride ingestion during tooth development, resulting in tooth discoloration ranging from white streaks to brown stains and cracks or pits in the tooth enamel."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006722"
    },
    {
      "id": 10068,
      "label": "anodontia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13714",
          "GARD:0005818",
          "ICD9:520.0",
          "MEDGEN:98313",
          "MESH:D000848",
          "MedDRA:10002583",
          "OMIM:206780",
          "Orphanet:99797",
          "SCTID:16958000",
          "UMLS:C0399352",
          "icd11.foundation:413433873"
        ],
        "synonyms": [
          "complete absence of teeth",
          "developmental absence of tooth",
          "total anodontia of permanent and deciduous teeth",
          "absence of permanent teeth",
          "anodontia of permanent dentition",
          "teeth, permanent, absence of"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "Anodontia is an extreme developmental dental anomaly characterized by the complete absence of all teeth."
      },
      "child_count": 6,
      "reference_id": "MONDO:0008797"
    },
    {
      "id": 11285,
      "label": "taurodontism",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5714,
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "HP:0000679",
          "MEDGEN:75596",
          "MESH:C536946",
          "OMIM:272700",
          "Orphanet:3289",
          "SCTID:51744007",
          "UMLS:C0266039",
          "icd11.foundation:356382747"
        ],
        "synonyms": [
          "taurodontism",
          "taurodontism (disease)",
          "Bull teeth",
          "large pulp chambers in the molars"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "Taurodontism is a dental anomaly characterized by an elongated pulp chamber, displaced toward the apical floor of the tooth with no constriction at the level of the cemento-enamel junction, and short roots. It most frequently affects permanent molar teeth. Taurodontism increases the risk of pulp exposure. It can be isolated or associated with certain syndromes such as Down syndrome, amelogenesis imperfecta, and Klinefelter syndrome."
      },
      "child_count": 0,
      "reference_id": "MONDO:0010098"
    },
    {
      "id": 18785,
      "label": "dentinogenesis imperfecta",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4154",
          "GARD:0006258",
          "HP:0000703",
          "ICD9:520.5",
          "MEDGEN:8313",
          "MESH:D003811",
          "MedDRA:10054013",
          "NCIT:C84667",
          "Orphanet:49042",
          "SCTID:196286005",
          "UMLS:C0011436",
          "icd11.foundation:2090257992"
        ],
        "synonyms": [
          "DGI",
          "DGI without OI",
          "DI",
          "dentinogenesis imperfecta",
          "dentinogenesis imperfecta (disease)",
          "dentinogenesis imperfecta without osteogenesis imperfecta",
          "non-syndromic DGI",
          "non-syndromic dentinogenesis imperfecta",
          "opalescent teeth without OI",
          "opalescent teeth without osteogenesis imperfecta"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "Dentinogenesis imperfecta (DGI) is a hereditary dentin defect characterized by abnormal dentin structure resulting in abnormal tooth development."
      },
      "child_count": 2,
      "reference_id": "MONDO:0018849"
    },
    {
      "id": 20417,
      "label": "odontogenic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7231,
        8422,
        20434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027878",
          "ICDO:9270/1",
          "MEDGEN:10426",
          "MESH:D009808",
          "NCIT:C3286",
          "UMLS:C0028880"
        ],
        "synonyms": [
          "calcareous tooth neoplasm",
          "calcareous tooth neoplasm (disease)",
          "calcareous tooth tumor",
          "calcareous tooth tumour",
          "neoplasm of calcareous tooth",
          "odontogenic neoplasm",
          "odontogenic tumor",
          "odontogenic tumour",
          "tumor of calcareous tooth",
          "tumour of calcareous tooth"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm arising from tooth-forming tissues. It occurs in the maxillofacial skeleton or the gingiva. Benign tumors are slow growing and are not associated with specific clinical symptoms. Pain is absent or slight. Malignant tumors are usually associated with rapid swelling and pain."
      },
      "child_count": 12,
      "reference_id": "MONDO:0021192"
    },
    {
      "id": 26377,
      "label": "dental radicular dysplasia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5714,
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "OMIM:621434"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0980763"
    }
  ],
  "roots": [
    {
      "id": 6893,
      "label": "skeletal system disorder"
    },
    {
      "id": 8301,
      "label": "mouth disorder"
    }
  ]
}