{
  "id": 8423,
  "label": "Treponema infectious disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007000",
  "properties": {
    "xrefs": [
      "EFO:1001217",
      "GARD:0007798",
      "MESH:D014211",
      "NCIT:C85197"
    ],
    "synonyms": [
      "Treponema caused disease or disorder",
      "Treponema disease or disorder",
      "Bejels",
      "bejel",
      "Treponemal infection",
      "infection, Treponemal",
      "infections, Treponemal"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "An disease caused by infection with Treponema."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 7014,
      "label": "bacterial sexually transmitted disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839,
        20726
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003955",
          "MEDGEN:20728",
          "MESH:D015231",
          "UMLS:C0036917"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Bacterial diseases that are potentially transmitted or propagated by sexual conduct."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005323"
    },
    {
      "id": 20723,
      "label": "gram-negative bacterial infections",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:041.85",
          "MEDGEN:88406",
          "MESH:D016905",
          "SCTID:371583007",
          "UMLS:C0085423"
        ],
        "synonyms": [
          "bacterial infection, gram-negative",
          "bacterial infections, gram negative",
          "bacterial infections, gram-negative",
          "bacterial infections, gramme negative",
          "gram negative bacterial infections",
          "gram-negative bacterial infection",
          "gramme negative bacterial infections",
          "infection, gram-negative bacterial",
          "infections, gram negative bacterial",
          "infections, gram-negative bacterial",
          "infections, gramme negative bacterial"
        ],
        "definition": "Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method."
      },
      "child_count": 15,
      "reference_id": "MONDO:0021678"
    },
    {
      "id": 20765,
      "label": "spirochaetales infections",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0009567",
          "MEDGEN:11556",
          "MESH:D013145",
          "UMLS:C0037974"
        ],
        "synonyms": [
          "INFECT SPIROCHAETALES",
          "INFECT SPIROCHETE",
          "Infection, Spirochaetales",
          "Infection, Spirochete",
          "Infections, Spirochaetales",
          "Infections, Spirochete",
          "SPIROCHAETALES INFECT",
          "SPIROCHETE INFECT",
          "Spirochaetales Infection",
          "Spirochaetales Infections",
          "Spirochetal infection",
          "Spirochete Infection",
          "Spirochete Infections",
          "Spirochetosis"
        ],
        "definition": "Infections with bacteria of the order SPIROCHAETALES."
      },
      "child_count": 4,
      "reference_id": "MONDO:0021839"
    }
  ],
  "children": [
    {
      "id": 3205,
      "label": "syphilitic meningitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8423,
        23046
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10073",
          "GARD:0008731",
          "ICD9:094.2",
          "MEDGEN:57546",
          "MESH:C536775",
          "SCTID:301086002",
          "UMLS:C0153166"
        ],
        "synonyms": [
          "Treponema caused infectious meningitis",
          "Treponema infectious meningitis",
          "meningeal syphilis",
          "meningitis, syphilitic",
          "syphilitic aseptic meningitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An infectious meningitis caused by infection with Treponema."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000936"
    },
    {
      "id": 3206,
      "label": "syphilitic encephalitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8423,
        19721
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10081",
          "GARD:0022849",
          "ICD9:094.81",
          "MEDGEN:509177",
          "SCTID:26135000",
          "UMLS:C0153168"
        ],
        "synonyms": [
          "Treponema caused encephalitis",
          "Treponema encephalitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An encephalitis caused by infection with Treponema."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000937"
    },
    {
      "id": 3248,
      "label": "pinta disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2837,
        8423,
        21329
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1022",
          "GARD:0007397",
          "ICD10CM:A67",
          "ICD9:103",
          "ICD9:103.0",
          "ICD9:103.1",
          "ICD9:103.2",
          "ICD9:103.3",
          "ICD9:103.9",
          "MEDGEN:45926",
          "MESH:D010874",
          "NCIT:C85011",
          "NORD:1580",
          "SCTID:22064009",
          "UMLS:C0031946",
          "icd11.foundation:1465035083"
        ],
        "synonyms": [
          "Pinta",
          "pinta",
          "Azul",
          "Carate",
          "Empeines",
          "Lota",
          "Mal del pinto",
          "Tina",
          "endemic treponematosis caused by Treponema carateum",
          "infection by Treponema carateum"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An endemic bacterial infection caused by Treponema carateum. It is manifested with chronic cutaneous lesions. The early lesions consist of papules and erythematous plaques. The late lesions consist of hypochromic, achromic, hyperpigmented and atrophic lesions. The late skin lesions may cause destruction of bones and cartilage and produce disfiguring changes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000979"
    },
    {
      "id": 7568,
      "label": "syphilis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2837,
        8423
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4166",
          "EFO:0007504",
          "GARD:0027732",
          "ICD9:097.9",
          "MEDGEN:21447",
          "MESH:D013587",
          "MedDRA:10062120",
          "NCIT:C35055",
          "SCTID:76272004",
          "UMLS:C0039128",
          "icd11.foundation:455894495"
        ],
        "synonyms": [
          "Treponema pallidum caused disease or disorder",
          "Treponema pallidum disease or disorder",
          "Treponema pallidum infectious disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A contagious bacterial infection caused by the spirochete Treponema pallidum. It is a sexually transmitted disorder, although it can also be transmitted from the mother to the fetus in utero. Typically, it is initially manifested with a single sore which heals without treatment. If the infection is left untreated, the initial stage is followed by skin rash and mucous membrane lesions. A late stage follows, which is characterized by damage of the internal organs, including the nervous system."
      },
      "child_count": 20,
      "reference_id": "MONDO:0005976"
    }
  ],
  "roots": [
    {
      "id": 7014,
      "label": "bacterial sexually transmitted disease"
    },
    {
      "id": 20723,
      "label": "gram-negative bacterial infections"
    },
    {
      "id": 20765,
      "label": "spirochaetales infections"
    }
  ]
}