{
  "id": 8430,
  "label": "uremia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007008",
  "properties": {
    "xrefs": [
      "DOID:4676",
      "EFO:1001226",
      "MEDGEN:12008",
      "MESH:D014511",
      "MedDRA:10046369",
      "SCTID:44730006",
      "UMLS:C0041948"
    ],
    "synonyms": [
      "uremia of renal origin"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of renal insufficiency. Most uremic toxins are end products of protein or nitrogen catabolism, such as urea or creatinine. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 3356,
      "label": "kidney failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1074",
          "EFO:1002048",
          "ICD9:404.12",
          "ICD9:404.13",
          "ICD9:586",
          "MEDGEN:11177",
          "MESH:D051437",
          "NCIT:C4376",
          "SCTID:42399005",
          "UMLS:C0035078",
          "icd11.foundation:761526554"
        ],
        "synonyms": [
          "failure, renal",
          "renal failure",
          "renal failure syndrome",
          "renal insufficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001106"
    }
  ],
  "children": [
    {
      "id": 5070,
      "label": "uremic neuropathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6950,
        8430
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4675",
          "GARD:0023359",
          "ICD9:357.4",
          "MEDGEN:75707",
          "NCIT:C27055",
          "SCTID:11659006",
          "UMLS:C0268708"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Neuropathy resulting from uremia."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003084"
    }
  ],
  "roots": [
    {
      "id": 3356,
      "label": "kidney failure"
    }
  ]
}