{
  "id": 8446,
  "label": "metabolic dysfunction-associated steatohepatitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007027",
  "properties": {
    "xrefs": [
      "DOID:0080547",
      "EFO:1001249",
      "ICD10CM:K75.81",
      "MEDGEN:469032",
      "MedDRA:10053219",
      "NCIT:C84445",
      "UMLS:C3241937",
      "icd11.foundation:1884917970"
    ],
    "synonyms": [
      "MASH",
      "NASH",
      "NASH - nonalcoholic steatohepatitis",
      "non-alcoholic steatohepatitis",
      "nonalcoholic steatohepatitis"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Metabolic dysfunction-associated steatohepatitis (MASH, formerly known as nonalcoholic steatohepatitis or NASH) is a type of fatty liver disease. It often develops due to a metabolic disorder, such as obesity or diabetes, resulting in a toxic buildup of fat in the liver. It is the most severe form of metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as nonalcoholic fatty liver disease or NAFLD)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4367,
      "label": "hepatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6878,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2237",
          "ICD9:570",
          "ICD9:571.4",
          "ICD9:571.40",
          "ICD9:571.41",
          "MEDGEN:5515",
          "MESH:D006505",
          "NCIT:C3095",
          "SCTID:197268000",
          "UMLS:C0019158"
        ],
        "synonyms": [
          "Hepatitis",
          "hepatitis",
          "inflammation of liver",
          "liver inflammation",
          "acute and subacute liver necrosis",
          "acute hepatitis",
          "acute/subac. necrosis of liver",
          "animal hepatitis",
          "chronic hepatitis",
          "chronic persistent hepatitis",
          "Hepatitides"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An active inflammatory process affecting the liver for more than six months. Causes include viral infections, autoimmune disorders, drugs, and metabolic disorders."
      },
      "child_count": 18,
      "reference_id": "MONDO:0002251"
    },
    {
      "id": 14245,
      "label": "metabolic dysfunction-associated steatotic liver disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6557
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080208",
          "DOID:0080546",
          "EFO:0003095",
          "ICD9:571.8",
          "MEDGEN:96033",
          "MESH:D065626",
          "MedDRA:10029530",
          "NCIT:C84444",
          "Orphanet:33271",
          "SCTID:197315008",
          "UMLS:C0400966",
          "icd11.foundation:1912806631"
        ],
        "synonyms": [
          "MASLD",
          "NAFLD",
          "NAFLD - nonalcoholic fatty liver disease",
          "fatty liver disease, nonalcoholic",
          "non-alcoholic fatty liver",
          "non-alcoholic fatty liver disease",
          "nonalcoholic fatty liver disease",
          "NAFLD1",
          "fatty liver disease, nonalcoholic, susceptibility to, 1",
          "liver disease, alcoholic, susceptibility to, 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as nonalcoholic fatty liver disease or NAFLD) is a type of liver disease that is not caused by alcohol. It typically does not cause symptoms in the early stages, but it can cause health problems due to fat accumulation, inflammation, and scarring in the liver."
      },
      "child_count": 2,
      "reference_id": "MONDO:0013209"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4367,
      "label": "hepatitis"
    },
    {
      "id": 14245,
      "label": "metabolic dysfunction-associated steatotic liver disease"
    }
  ]
}