{
  "id": 8478,
  "label": "acrorenal syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007059",
  "properties": {
    "xrefs": [
      "DOID:0060347",
      "GARD:0000514",
      "MEDGEN:501193",
      "MESH:C563159",
      "OMIM:102520",
      "Orphanet:971",
      "SCTID:720458005",
      "UMLS:C3495490",
      "icd11.foundation:1948375645"
    ],
    "synonyms": [
      "acrorenal syndrome"
    ],
    "definition": "Acrorenal syndrome comprises a wide spectrum of congenital malformative disorders characterized by the co-occurrence of distal limb anomalies (usually bilateral cleft feet and/or hands) and renal defects (e.g. unilateral or bilateral agenesis), that can be associated with a variety of other anomalies such as those of genitourinary tract (genital anomalies, ureteral hypoplasias, vesicoureteral reflux), abdominal well defects, intestinal atresias, and lung malformations. Familial cases have been reported in which an autosomal recessive inheritance was suspected."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 16089,
      "label": "multiple congenital anomalies/dysmorphic syndrome without intellectual disability",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18951
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019833",
          "MEDGEN:1842829",
          "Orphanet:102285",
          "UMLS:C5680373"
        ],
        "synonyms": [
          "MCA without intellectual disability",
          "multiple congenital anomalies without intellectual disability with or without dysmorphism"
        ]
      },
      "child_count": 168,
      "reference_id": "MONDO:0015161"
    }
  ],
  "children": [
    {
      "id": 9992,
      "label": "acrorenal syndrome, autosomal recessive",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7611,
        8478
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015130",
          "MEDGEN:163241",
          "MESH:C535666",
          "OMIM:201310",
          "UMLS:C0796290"
        ],
        "synonyms": [
          "acrorenal syndrome, autosomal recessive",
          "autosomal recessive acrorenal syndrome",
          "Curran syndrome",
          "acrorenal syndrome autosomal recessive",
          "acrorenal syndrome recessive"
        ],
        "definition": "Autosomal recessive form of acrorenal syndrome."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008719"
    }
  ],
  "roots": [
    {
      "id": 16089,
      "label": "multiple congenital anomalies/dysmorphic syndrome without intellectual disability"
    }
  ]
}