{
  "id": 8541,
  "label": "tooth agenesis, selective, 1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007129",
  "properties": {
    "xrefs": [
      "GARD:0018244",
      "MEDGEN:483482",
      "OMIM:106600",
      "UMLS:C3489529"
    ],
    "synonyms": [
      "MSX1 tooth agenesis",
      "MSX1-related tooth agenesis with or without orofacial cleft",
      "tooth agenesis caused by mutation in MSX1",
      "tooth agenesis, selective, 1",
      "tooth agenesis, selective, 1, with or without orofacial cleft",
      "tooth agenesis, selective, type 1",
      "STHAG1",
      "hypodontia/oligodontia 1",
      "second premolars and third molars, absence of",
      "tooth agenesis, familial"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      }
    ],
    "definition": "Any tooth agenesis in which the cause of the disease is a mutation in the MSX1 gene characterized by varying severity of tooth agenesis that may be seen in combination with orofacial clefting in some individuals."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7142,
      "label": "tooth agenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        8422
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050591",
          "EFO:0005410",
          "ICD10CM:K00.0",
          "ICD9:520.0",
          "MEDGEN:43794",
          "OMIMPS:106600",
          "Orphanet:2227",
          "Orphanet:99798",
          "SCTID:64969001",
          "UMLS:C0020608",
          "icd11.foundation:1559717619"
        ],
        "synonyms": [
          "hypodontia",
          "selective tooth agenesis",
          "tooth agenesis, selective",
          "oligodontia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A tooth disease characterized by failure to develop one or more missing teeth."
      },
      "child_count": 24,
      "reference_id": "MONDO:0005486"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7142,
      "label": "tooth agenesis"
    }
  ]
}