{
  "id": 8561,
  "label": "arteriovenous malformations of the brain",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007154",
  "properties": {
    "xrefs": [
      "DOID:0060688",
      "GARD:0003020",
      "MEDGEN:214590",
      "MESH:D002538",
      "NANDO:2100229",
      "NANDO:2200851",
      "NCIT:C2936",
      "OMIM:108010",
      "Orphanet:46724",
      "SCTID:234142008",
      "UMLS:C0917804",
      "icd11.foundation:153256729"
    ],
    "synonyms": [
      "arteriovenous malformation of the brain, somatic",
      "arteriovenous malformations of the brain",
      "cerebral arteriovenous malformation",
      "intracranial arteriovenous malformation",
      "intracranial haemorrhage in brain cerebrovascular malformations, susceptibility to, somatic mutation",
      "intracranial hemorrhage in brain cerebrovascular malformations, susceptibility to, somatic mutation",
      "Bavm",
      "cerebral arteriovenous malformations",
      "intracranial AVM",
      "intracranial haemorrhage in brain arteriovenous malformations, susceptibility to",
      "intracranial hemorrhage in brain arteriovenous malformations, susceptibility to"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Cerebral arteriovenous malformation (AVM) is a congenital malformative communication between the veins and the arteries in the brain in the form of a nidus, an anatomical structure composed of dilated and tangled supplying arterioles and drainage veins with no intervening capillary bed, that can be asymptomatic or cause, depending on the location and the size of the AVM, headaches of varying severity, generalized or focal seizures, focalneurological defects (weakness, numbness, speech difficulties, vision loss) or potentially fatal intracranial hemorrhage in case the AVM ruptures."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3493,
      "label": "arteriovenous hemangioma/malformation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7994
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:0571-2717",
          "DOID:11294",
          "HP:0100026",
          "ICDO:9123/0",
          "MEDGEN:137780",
          "MESH:D001165",
          "NCIT:C2882",
          "SCTID:233982006",
          "UMLS:C0334533"
        ],
        "synonyms": [
          "arteriovenous angioma",
          "arteriovenous hemangioma",
          "arteriovenous hemangioma/malformation",
          "racemose aneurysm (morphologic abnormality)",
          "racemose hemangioma (morphologic abnormality)",
          "arteriovenous malformation",
          "cirsoid aneurysm"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A benign vascular lesion characterized by the presence of a complex network of communicating arterial and venous vascular structures."
      },
      "child_count": 7,
      "reference_id": "MONDO:0001256"
    },
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3493,
      "label": "arteriovenous hemangioma/malformation"
    },
    {
      "id": 5714,
      "label": "hereditary disease"
    }
  ]
}