{
  "id": 8593,
  "label": "gastroesophageal reflux disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007186",
  "properties": {
    "xrefs": [
      "DOID:8534",
      "EFO:0003948",
      "ICD9:530.81",
      "MEDGEN:6553",
      "MESH:D005764",
      "NCIT:C26781",
      "OMIM:109350",
      "SCTID:235595009",
      "UMLS:C0017168",
      "icd11.foundation:1391387859"
    ],
    "synonyms": [
      "GERD",
      "acid reflux",
      "gastroesophageal reflux",
      "gastroesophageal reflux disease",
      "gastroesophageal reflux, paediatric",
      "gastroesophageal reflux, pediatric",
      "ger"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5629,
      "label": "esophageal disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23495
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6050",
          "EFO:0009544",
          "ICD9:530",
          "ICD9:530.2",
          "ICD9:530.20",
          "ICD9:530.9",
          "MEDGEN:8693",
          "MESH:D004935",
          "NCIT:C3027",
          "SCTID:30811009",
          "SCTID:37657006",
          "UMLS:C0014852",
          "icd11.foundation:1594312948"
        ],
        "synonyms": [
          "disease of esophagus",
          "disease of oesophagus",
          "disease or disorder of esophagus",
          "disease or disorder of oesophagus",
          "disorder of esophagus",
          "disorder of oesophagus",
          "esophageal disorder",
          "esophagus disease",
          "esophagus disease or disorder",
          "oesophagus disease",
          "oesophagus disease or disorder",
          "esophageal ulcer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas."
      },
      "child_count": 20,
      "reference_id": "MONDO:0003749"
    },
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    },
    {
      "id": 6115,
      "label": "stomach disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6151
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:76",
          "EFO:0009608",
          "ICD9:537.89",
          "ICD9:537.9",
          "MEDGEN:21329",
          "MESH:D013272",
          "NCIT:C26886",
          "SCTID:29384001",
          "UMLS:C0038354",
          "icd11.foundation:1264914040"
        ],
        "synonyms": [
          "disease of stomach",
          "disease or disorder of stomach",
          "disorder of stomach",
          "stomach disease",
          "stomach disease or disorder",
          "stomach disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A disease involving the stomach."
      },
      "child_count": 19,
      "reference_id": "MONDO:0004298"
    }
  ],
  "children": [
    {
      "id": 8192,
      "label": "duodenogastric reflux",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4880,
        8593
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4071",
          "EFO:1000909",
          "MEDGEN:4420",
          "MESH:D004383",
          "MedDRA:10060865",
          "UMLS:C0013299"
        ],
        "synonyms": [
          "duodenogastric reflux (finding)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Retrograde flow of duodenal contents (bile acids; pancreatic juice) into the stomach."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006735"
    }
  ],
  "roots": [
    {
      "id": 5629,
      "label": "esophageal disorder"
    },
    {
      "id": 5714,
      "label": "hereditary disease"
    },
    {
      "id": 6115,
      "label": "stomach disorder"
    }
  ]
}