{
  "id": 8649,
  "label": "Caffey disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007244",
  "properties": {
    "xrefs": [
      "DOID:4257",
      "GARD:0001051",
      "ICD9:756.59",
      "MEDGEN:43781",
      "MESH:D006958",
      "NCIT:C118423",
      "OMIM:114000",
      "Orphanet:1310",
      "SCTID:24752008",
      "UMLS:C0020497"
    ],
    "synonyms": [
      "Caffey disease",
      "infantile cortical hyperostosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Caffey disease is an osteosclerotic dysplasia characterized by acute inflammation with massive subperiosteal new bone formation usually involving the diaphyses of the long bones, as well as the ribs, mandible, scapulae, and clavicles. The disease is associated with fever, irritability pain and soft tissue swelling, with onset around the age of 2 months and resolving spontaneously by the age of 2 years. However, prenatal disease onset has also been described."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4308,
      "label": "hyperostosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3151
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:205",
          "ICD10CM:M89.3",
          "ICD9:733.99",
          "MEDGEN:9366",
          "MESH:D015576",
          "NCIT:C34712",
          "SCTID:203514008",
          "UMLS:C0020492"
        ],
        "synonyms": [
          "bone hypertrophy",
          "hypertrophy of bone",
          "hypertrophy of bone (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Excessive thickening of bone."
      },
      "child_count": 9,
      "reference_id": "MONDO:0002185"
    },
    {
      "id": 4665,
      "label": "bone inflammation disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7061
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3342",
          "MEDGEN:10492",
          "MESH:D010000",
          "SCTID:274144001",
          "UMLS:C0029400"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Inflammation of the bone."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002614"
    },
    {
      "id": 19477,
      "label": "neonatal osteosclerotic dysplasia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7171
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019199",
          "MEDGEN:721998",
          "Orphanet:93443",
          "SCTID:389236000",
          "UMLS:C1300205"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0019702"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4308,
      "label": "hyperostosis"
    },
    {
      "id": 4665,
      "label": "bone inflammation disease"
    },
    {
      "id": 19477,
      "label": "neonatal osteosclerotic dysplasia"
    }
  ]
}