{
  "id": 8659,
  "label": "breast cancer",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007254",
  "properties": {
    "xrefs": [
      "DOID:1612",
      "ICD10CM:C50",
      "ICD9:174.8",
      "MEDGEN:651",
      "NCIT:C9335",
      "SCTID:254837009",
      "UMLS:C0006142",
      "icd11.foundation:1047754165"
    ],
    "synonyms": [
      "breast tumor",
      "breast tumour",
      "mammary tumor",
      "mammary tumour",
      "breast cancer",
      "cancer of breast",
      "malignant breast neoplasm",
      "malignant breast tumor",
      "malignant breast tumour",
      "malignant neoplasm of breast",
      "malignant neoplasm of the breast",
      "malignant tumor of breast",
      "malignant tumor of the breast",
      "malignant tumour of breast",
      "malignant tumour of the breast",
      "primary breast cancer"
    ],
    "categories": [
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "A primary or metastatic malignant neoplasm involving the breast. The vast majority of cases are carcinomas arising from the breast parenchyma or the nipple. Malignant breast neoplasms occur more frequently in females than in males."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 5215,
      "label": "thoracic cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        20518
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5093",
          "ICD10CM:C76.1",
          "ICD9:195.1",
          "MEDGEN:56320",
          "NCIT:C3576",
          "SCTID:188361007",
          "UMLS:C0153661"
        ],
        "synonyms": [
          "thoracic tumor",
          "thoracic tumour",
          "thorax neoplasm",
          "tumor of thorax",
          "tumour of thorax",
          "cancer of thoracic segment of trunk",
          "malignant neoplasm of the thorax",
          "malignant neoplasm of thoracic segment of trunk",
          "malignant neoplasm of thorax",
          "malignant thoracic neoplasm",
          "malignant thoracic segment of trunk neoplasm",
          "malignant thoracic tumor",
          "malignant thoracic tumour",
          "malignant tumor of the thorax",
          "malignant tumor of thorax",
          "malignant tumour of the thorax",
          "malignant tumour of thorax",
          "thoracic segment of trunk cancer"
        ],
        "definition": "A primary or metastatic malignant neoplasm affecting the tissues of the thorax."
      },
      "child_count": 16,
      "reference_id": "MONDO:0003274"
    },
    {
      "id": 20340,
      "label": "breast neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4708,
        20518
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003869",
          "ICD9:239.3",
          "MEDGEN:264172",
          "MESH:D001943",
          "NCIT:C2910",
          "ONCOTREE:BREAST",
          "SCTID:126926005",
          "UMLS:C1458155"
        ],
        "synonyms": [
          "breast neoplasm",
          "breast neoplasm (disease)",
          "breast tumor",
          "breast tumour",
          "neoplasm of breast",
          "neoplasm of the breast",
          "neoplasm, breast",
          "tumor of breast",
          "tumor of the breast",
          "tumour of breast",
          "tumour of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A benign or malignant neoplasm of the breast parenchyma. It can originate from the ducts, lobules or the breast adipose tissue. Breast neoplasms are much more common in females than males."
      },
      "child_count": 22,
      "reference_id": "MONDO:0021100"
    }
  ],
  "children": [
    {
      "id": 4568,
      "label": "malignant breast phyllodes tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8659,
        20291,
        22955
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3016",
          "EFO:0008545",
          "GARD:0023148",
          "MEDGEN:87543",
          "NCIT:C4504",
          "ONCOTREE:MPT",
          "SCTID:254844000",
          "UMLS:C0346154",
          "icd11.foundation:147026376"
        ],
        "synonyms": [
          "malignant phyllodes neoplasm",
          "phyllodes breast neoplasm",
          "phyllodes breast tumor",
          "phyllodes breast tumour",
          "phyllodes tumor, malignant (morphologic abnormality)",
          "breast phyllodes tumor, malignant",
          "malignant breast phyllodes neoplasm",
          "malignant breast phyllodes tumor",
          "malignant cystosarcoma phyllodes of breast",
          "malignant cystosarcoma phyllodes of the breast",
          "malignant mammary phyllodes neoplasm",
          "malignant mammary phyllodes tumor",
          "malignant phyllodes breast neoplasm",
          "malignant phyllodes neoplasm of breast",
          "malignant phyllodes neoplasm of the breast",
          "malignant phyllodes tumor (morphologic abnormality)",
          "malignant phyllodes tumor of breast",
          "malignant phyllodes tumor of the breast",
          "malignant phyllodes tumour (morphologic abnormality)",
          "malignant phyllodes tumour of breast",
          "malignant phyllodes tumour of the breast",
          "breast malignant phyllodes tumor",
          "breast malignant phyllodes tumour",
          "malignant cystosarcoma phyllodes",
          "malignant cystosarcoma phyllodes (morphologic abnormality)",
          "malignant phyllodes tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A phyllodes tumor of the breast characterized by infiltrative margins and a sarcomatous stromal component. The sarcomatous stroma usually displays features of fibrosarcoma. Liposarcomatous, osteosarcomatous, or rhabdomyosarcomatous elements may also be present."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002489"
    },
    {
      "id": 4569,
      "label": "breast sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8659,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3017",
          "GARD:0023149",
          "MEDGEN:87613",
          "NCIT:C4670",
          "ONCOTREE:PBS",
          "SCTID:278050001",
          "UMLS:C0349667"
        ],
        "synonyms": [
          "breast sarcoma",
          "sarcoma of breast",
          "sarcoma of the breast",
          "PBS"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A malignant mesenchymal neoplasm that arises from the breast. Representative examples include angiosarcoma, liposarcoma, leiomyosarcoma, rhabdomyosarcoma, and extraskeletal osteosarcoma."
      },
      "child_count": 14,
      "reference_id": "MONDO:0002490"
    },
    {
      "id": 4979,
      "label": "malignant breast melanoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6832,
        8659
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4364",
          "MEDGEN:138069",
          "NCIT:C8410",
          "SCTID:188050009",
          "UMLS:C0346787"
        ],
        "synonyms": [
          "breast melanoma",
          "breast melanoma (disease)",
          "malignant breast melanoma",
          "malignant melanoma of breast",
          "malignant melanoma of the breast",
          "melanoma (disease) of breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A melanoma that arises usually from the breast skin and less often from the breast glandular tissue. Primary breast melanomas are rare."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002975"
    },
    {
      "id": 5548,
      "label": "breast lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792,
        8659
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5826",
          "GARD:0023608",
          "MEDGEN:309939",
          "NCIT:C4671",
          "SCTID:278052009",
          "UMLS:C1704251"
        ],
        "synonyms": [
          "breast lymphoma",
          "lymphoma of breast",
          "lymphoma of the breast",
          "primary breast lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A lymphoma that arises from the breast. There is no history of extramammary breast lymphoma and ipsilateral axillary lymph node involvement does not exclude the diagnosis of primary breast lymphoma. Most patients present with a painless breast lump. The vast majority of cases are B-cell non-Hodgkin lymphomas. Diffuse large B-cell lymphoma, follicular lymphoma, and extranodal marginal zone B-cell lymphoma of mucosa associated lymphoid tissue are the most common types of primary non-Hodgkin lymphoma of the breast. Primary Hodgkin lymphoma of the breast is rare."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003661"
    },
    {
      "id": 6730,
      "label": "breast carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        8659
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3459",
          "EFO:0000305",
          "HP:0003002",
          "MEDGEN:146260",
          "NCIT:C4872",
          "SCTID:254838004",
          "UMLS:C0678222"
        ],
        "synonyms": [
          "breast cancer",
          "breast cancer, NOS",
          "cancer of breast",
          "cancer of the breast",
          "cancer, breast",
          "breast carcinoma",
          "carcinoma of breast",
          "carcinoma of the breast",
          "mammary carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the breast"
      },
      "child_count": 26,
      "reference_id": "MONDO:0004989"
    },
    {
      "id": 24233,
      "label": "salivary gland type cancer of the breast",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8659
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0012774",
          "MEDGEN:903115",
          "Orphanet:213557",
          "SCTID:716593008",
          "UMLS:C4274421",
          "icd11.foundation:2145246967"
        ],
        "synonyms": [
          "salivary gland type carcinoma of the breast"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A group of uncommon neoplasms, usually seen in the salivary glands but occurring in the breast, with a variable clinicopathologic spectrum and divided into those with myoepithelial differentiation and those without. This group includes mammary adenoid cystic carcinoma, adenoid cystic carcinoma, mucoepidermoid carcinoma, acinic cell carcinoma, polymorphous low-grade adenocarcinoma and oncocytic carcinoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100508"
    }
  ],
  "roots": [
    {
      "id": 5215,
      "label": "thoracic cancer"
    },
    {
      "id": 20340,
      "label": "breast neoplasm"
    }
  ]
}