{
  "id": 8697,
  "label": "ADan amyloidosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007297",
  "properties": {
    "xrefs": [
      "DOID:0070030",
      "GARD:0009169",
      "MEDGEN:396208",
      "MESH:C538209",
      "OMIM:117300",
      "Orphanet:97346",
      "UMLS:C1861735",
      "icd11.foundation:2086401830",
      "icd11.foundation:54507082"
    ],
    "synonyms": [
      "FDD",
      "HOOE",
      "Heredopathia Ophthalmootoencephalica",
      "cerebellar ataxia, cataract, deafness, and dementia Or psychosis",
      "cerebral amyloid angiopathy, ITM2B-related, type 2",
      "familial Danish dementia",
      "familial dementia, Danish type",
      "ITM2B-related cerebral amyloid angiopathy 2",
      "cerebellar ataxia, cataract, deafness, and dementia or psychosis",
      "cerebral amyloid angiopathy, ITM2B-RELATED, 2",
      "dementia, familial Danish"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A cerebral amyloid angiopathy characterized by ataxia, intention tremor, psychosis and dementia that has material basis in an autosomal dominant mutation of ITM2B on chromosome 13q14.2."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7260,
      "label": "cerebral amyloid angiopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        12183,
        18631,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9246",
          "EFO:0006790",
          "GARD:0010266",
          "ICD10CM:I68.0",
          "ICD9:277.39",
          "MEDGEN:267610",
          "MESH:D016657",
          "NCIT:C84625",
          "Orphanet:85458",
          "SCTID:230724001",
          "UMLS:C1510489"
        ],
        "synonyms": [
          "HCHWA",
          "dutch hereditary cerebral amyloid angiopathy",
          "hereditary cerebral haemorrhage with amyloidosis - Dutch type",
          "hereditary cerebral hemorrhage with amyloidosis - Dutch type",
          "CAA, familial",
          "cerebral amyloid angiopathy, familial",
          "cerebral amyloid angiopathy, genetic"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Hereditary cerebral hemorrhage with amyloidosis (HCHWA) describes a group of rare familial central nervous system disorders characterized by amyloid deposition in the cerebral blood vessels leading to hemorrhagic and non-hemorrhagic strokes, focal neurological deficits, and progressive cognitive decline eventually leading to dementia."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005620"
    },
    {
      "id": 18594,
      "label": "ITM2B amyloidosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18631,
        21292
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017741",
          "ICD9:277.39",
          "MEDGEN:82800",
          "Orphanet:439254",
          "SCTID:45639009",
          "UMLS:C0268393",
          "icd11.foundation:503091580"
        ],
        "synonyms": [
          "ITM2B-related amyloidosis",
          "ITM2B-related cerebral amyloid angiopathy",
          "familial cerebral amyloid angiopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 4,
      "reference_id": "MONDO:0018591"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7260,
      "label": "cerebral amyloid angiopathy"
    },
    {
      "id": 18594,
      "label": "ITM2B amyloidosis"
    }
  ]
}