{
  "id": 8798,
  "label": "Cryoglobulinemic vasculitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007407",
  "properties": {
    "xrefs": [
      "GARD:0006386",
      "ICD9:273.2",
      "MEDGEN:343814",
      "MESH:C565141",
      "MedDRA:10027756",
      "NORD:1452",
      "OMIM:123550",
      "Orphanet:91138",
      "SCTID:190815001",
      "UMLS:C1852456",
      "icd11.foundation:55133785"
    ],
    "synonyms": [
      "MC",
      "Mixed Cryoglobulinemia",
      "essential cryoglobulinemia",
      "essential mixed cryoglobulinemia",
      "mixed cryoglobulinemia",
      "primary cryoglobulinemia",
      "Meltzer syndrome",
      "cryoglobulinemia, familial mixed",
      "familial mixed cryoglobulinemia"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Mixed cryoglobulinemia (MC) is a rare multisystem disease characterized by the presence of circulating cryoprecipitable immune complexes in the serum, manifested clinically by a classical triad of purpura, weakness and arthralgia."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 16323,
      "label": "immune complex mediated vasculitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18813
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019984",
          "MEDGEN:1842565",
          "Orphanet:156149",
          "UMLS:C5680655"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0015491"
    }
  ],
  "children": [
    {
      "id": 19484,
      "label": "type II mixed cryoglobulinemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019220",
          "MEDGEN:1842376",
          "Orphanet:93554",
          "UMLS:C5680264"
        ],
        "synonyms": [
          "MC type II"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Type II mixed cryoglobulinemia, a relatively rare clinico-serological subtype of mixed cryoglobulinemia (MC), is an immune complex disorder characterized by purpura, weakness and arthralgia and defined immunochemically by cryoglobulins composed of polyclonal IgGs (autoantigens) and monoclonal IgM (autoantibody)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019726"
    },
    {
      "id": 19485,
      "label": "mixed cryoglobulinemia type III",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019221",
          "MEDGEN:1843066",
          "Orphanet:93555",
          "UMLS:C5680263"
        ],
        "synonyms": [
          "MC type III"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Type III mixed cryoglobulinemia, a relatively rare clinico-serological subtype of mixed cryoglobulinemia (MC), is an immune complex disorder characterized by purpura, weakness and arthralgia and defined immunochemically by cryoglobulins containing both polyclonal IgGs and polyclonal IgMs."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019727"
    }
  ],
  "roots": [
    {
      "id": 16323,
      "label": "immune complex mediated vasculitis"
    }
  ]
}