{
  "id": 8805,
  "label": "Gorham-Stout disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007414",
  "properties": {
    "xrefs": [
      "GARD:0006542",
      "ICD9:733.99",
      "MEDGEN:45248",
      "MedDRA:10071283",
      "NANDO:1200878",
      "NANDO:1200880",
      "NORD:1200",
      "OMIM:123880",
      "Orphanet:73",
      "SCTID:1515008",
      "UMLS:C0029438",
      "icd11.foundation:1318015458"
    ],
    "synonyms": [
      "Gorham disease",
      "Gorham syndrome",
      "Gorham-Stout disease",
      "idiopathic massive osteolysis",
      "progressive massive osteolysis",
      "vanishing bone disease",
      "cystic angiomatosis of bone diffuse",
      "cystic angiomatosis of bone, diffuse",
      "osteolysis massive",
      "osteolysis, massive"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Gorham-Stout disease (GSD) is a rare disease of massive osteolysis associated with proliferation and dilation of lymphatic vessels. GSD may affect any bone in the body and can be monostotic or polyostotic. Symptoms at presentation are dependent upon the location(s) of the disease; the most common symptom is localized pain. The disease may be discovered after a pathological fracture."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4167,
      "label": "lymphangioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3034,
        22949
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1475",
          "ICD9:228.1",
          "ICDO:9170/0",
          "MEDGEN:6153",
          "MESH:D008202",
          "NANDO:2201032",
          "NCIT:C8965",
          "Orphanet:2415",
          "SCTID:254836000",
          "SCTID:400178008",
          "UMLS:C0024221"
        ],
        "synonyms": [
          "benign lymphangioma (morphologic abnormality)",
          "lymphangioma",
          "lymphangioma, benign",
          "congenital lymphangioma",
          "LM"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A benign lesion composed of dilated lymphatic channels. Painless swelling is the usual clinical manifestation."
      },
      "child_count": 24,
      "reference_id": "MONDO:0002013"
    },
    {
      "id": 5126,
      "label": "disappearing bone disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4837",
          "ICD9:733.09",
          "MEDGEN:45247",
          "NANDO:1200878",
          "NANDO:1200880",
          "SCTID:240161003",
          "UMLS:C0029436"
        ],
        "synonyms": [
          "Gorham's disease",
          "massive osteolysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "Syndromes of bone destruction where the cause is not obvious such as neoplasia, infection, or trauma. The destruction follows various patterns: massive (Gorham disease), multicentric (hajdu-cheney syndrome), or carpal/tarsal."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003157"
    },
    {
      "id": 7203,
      "label": "rheumatic disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1575",
          "EFO:0005755",
          "ICD9:729.0",
          "MEDGEN:3157",
          "MESH:D012216",
          "NANDO:2100151",
          "NANDO:2100152",
          "NCIT:C27204",
          "SCTID:396332003",
          "UMLS:C0009326",
          "Wikipedia:Rheumatism"
        ],
        "synonyms": [
          "rheumatic disease",
          "rheumatologic disorder",
          "collagen disease",
          "collagen vascular disease",
          "connective tissue disease",
          "disease, rheumatic",
          "diseases, rheumatic",
          "enthesopathies",
          "enthesopathy",
          "inflammatory rheumatism",
          "musculoskeletal pain disorder",
          "rheumatism"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Inflammatory and degenerative diseases of connective tissue structures, such as arthritis."
      },
      "child_count": 30,
      "reference_id": "MONDO:0005554"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4167,
      "label": "lymphangioma"
    },
    {
      "id": 5126,
      "label": "disappearing bone disease"
    },
    {
      "id": 7203,
      "label": "rheumatic disorder"
    }
  ]
}