{
  "id": 8981,
  "label": "laurin-Sandrow syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007615",
  "properties": {
    "xrefs": [
      "DOID:0111350",
      "GARD:0000155",
      "MEDGEN:340697",
      "MESH:C535689",
      "OMIM:135750",
      "Orphanet:2378",
      "SCTID:715440003",
      "UMLS:C1851100",
      "icd11.foundation:671594481"
    ],
    "synonyms": [
      "Sandrow syndrome",
      "laurin-Sandrow syndrome",
      "mirror hands and feets-nasal defects syndrome",
      "LSS",
      "fibula and ulna, Duplication of, with absence of tibia and radius",
      "fibula ulna duplication tibia radius absence",
      "laurin Sandrow syndrome",
      "laurin-Sandrow syndrome, segmental",
      "mirror hands and feet with nasal defects",
      "mirror-Image polydactyly",
      "tetramelic mirror-Image polydactyly"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Laurin-Sandrow syndrome (LSS) is characterized by complete polysyndactyly of the hands, mirror feet and nose anomalies (hypoplasia of the nasal alae and short columella), often associated with ulnar and/or fibular duplication (and sometimes tibial agenesis). It has been described in less than 20 cases. Some cases with the same clinical signs but without nasal defects have also been reported, and may represent the same entity. The etiology of LSS is unknown. Different modes of inheritance have been suggested."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18956,
      "label": "congenital limb malformation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19507
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:68378"
        ],
        "synonyms": [
          "congenital limb malformation"
        ]
      },
      "child_count": 107,
      "reference_id": "MONDO:0019054"
    },
    {
      "id": 24804,
      "label": "polydactyly-syndactyly-triphalangism",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18360,
        20258,
        20259
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026428"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Any skeletal dysplasia that is characterizedby polydactyly, syndactyly and triphalangism, where a digit has three phalanges instead of two."
      },
      "child_count": 84,
      "reference_id": "MONDO:0800066"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18956,
      "label": "congenital limb malformation"
    },
    {
      "id": 24804,
      "label": "polydactyly-syndactyly-triphalangism"
    }
  ]
}