{
  "id": 9038,
  "label": "goiter, multinodular 1, with or without Sertoli-Leydig cell tumors",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007681",
  "properties": {
    "xrefs": [
      "GARD:0017278",
      "ICD9:240.0",
      "MEDGEN:86230",
      "MESH:C562732",
      "OMIM:138800",
      "Orphanet:276399",
      "SCTID:267369002",
      "UMLS:C0302859"
    ],
    "synonyms": [
      "euthyroid goiter",
      "euthyroid goitre",
      "simple goiter",
      "simple goitre",
      "FMNG",
      "MNG1",
      "familial MNG",
      "goiter, multinodular 1, with or without Sertoli-Leydig cell tumors",
      "goiter, nontoxic, with Intrathyroidal calcification",
      "multinodular goiter, adolescent"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Any multinodular goiter in which the cause of the disease is a mutation in the DICER1 gene."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2848,
      "label": "multinodular goiter",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        8310
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050489",
          "MEDGEN:87431",
          "NCIT:C131438",
          "OMIMPS:138800",
          "SCTID:237570007",
          "UMLS:C0342208"
        ],
        "synonyms": [
          "goiter, multinodular"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Nodular goiter characterized by more than one discrete tissue mass."
      },
      "child_count": 6,
      "reference_id": "MONDO:0000334"
    },
    {
      "id": 16218,
      "label": "hereditary neoplastic syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        20011,
        20301
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019921",
          "MEDGEN:14326",
          "MESH:D009386",
          "NCIT:C3266",
          "Orphanet:140162",
          "SCTID:699346009",
          "UMLS:C0027672"
        ],
        "synonyms": [
          "cancer syndrome, hereditary",
          "cancer syndromes, hereditary",
          "familial neoplastic syndrome",
          "familial tumor syndrome",
          "familial tumour syndrome",
          "hereditary cancer syndrome",
          "hereditary cancer syndromes",
          "hereditary neoplastic syndrome",
          "hereditary neoplastic syndromes",
          "hereditary tumor syndrome",
          "hereditary tumour syndrome",
          "inherited cancer syndrome",
          "inherited cancer-predisposing syndrome",
          "neoplastic syndrome, hereditary",
          "syndrome, hereditary cancer",
          "syndrome, hereditary neoplastic",
          "syndromes, hereditary cancer",
          "syndromes, hereditary neoplastic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "The inherited predisposition toward getting a tumor."
      },
      "child_count": 351,
      "reference_id": "MONDO:0015356"
    },
    {
      "id": 23957,
      "label": "DICER1-related tumor predisposition",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081063",
          "GARD:0010734",
          "ICD9:199.1",
          "MEDGEN:825667",
          "NCIT:C123317",
          "Orphanet:284343",
          "SCTID:702411003",
          "UMLS:C3839822"
        ],
        "synonyms": [
          "DICER1 syndrome",
          "PPB familial tumour susceptibility syndrome",
          "PPBFTDS",
          "pleuro-pulmonary blastoma familial tumour susceptibility syndrome",
          "pleuropulmonary blastoma familial tumour susceptibility syndrome",
          "DICER1-related pleuropulmonary blastoma",
          "DICER1-related pleuropulmonary blastoma cancer predisposition syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "Pathogenic germline variation in DICER1 confers an autosomal dominant predisposition to tumor formation at multiple primary sites, including pleuropulmonary blastoma, pulmonary cysts, thyroid gland neoplasia, ovarian tumors, and cystic nephroma. Other syndromic features such as macrocephaly have been described."
      },
      "child_count": 4,
      "reference_id": "MONDO:0100216"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2848,
      "label": "multinodular goiter"
    },
    {
      "id": 16218,
      "label": "hereditary neoplastic syndrome"
    },
    {
      "id": 23957,
      "label": "DICER1-related tumor predisposition"
    }
  ]
}