{
  "id": 9047,
  "label": "Guillain-Barre syndrome, familial",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007691",
  "properties": {
    "xrefs": [
      "EFO:0009538",
      "GARD:0018211",
      "MEDGEN:901636",
      "MedDRA:10057645",
      "NANDO:1200030",
      "NANDO:2100251",
      "NANDO:2200905",
      "OMIM:139393",
      "SCTID:716723000",
      "UMLS:C4083008"
    ],
    "synonyms": [
      "AIDP",
      "Guillain-Barre syndrome, familial",
      "neuropathy, inflammatory demyelinating",
      "polyneuropathy, inflammatory demyelinating, acute",
      "GBS"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A form of Guillain-Barre syndrome (GBS) that occurs in persons or families with a genetic predisposition to the acute or chronic forms of GBS. Note that GBS is considered to be a complex multifactorial disorder with both genetic and environmental factors, and families with clear Mendelian inheritance have been rarely reported: a mutation in the PMP22 gene (601097) on chromosome 17 was identified in a single family with the acute (AIDP) and chronic (CIDP) forms of inflammatory demyelinating polyneuropathy."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16801,
      "label": "Guillain-Barre syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3006,
        4370
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12842",
          "EFO:0007292",
          "GARD:0006554",
          "ICD10CM:G61.0",
          "MEDGEN:5399",
          "MESH:D020275",
          "MedDRA:10018767",
          "NCIT:C116345",
          "Orphanet:2103",
          "SCTID:40956001",
          "UMLS:C0018378"
        ],
        "synonyms": [
          "GBS",
          "Guillain Barre syndrome",
          "Guillain Barré syndrome",
          "Guillain-Barre-Strohl syndrome",
          "Guillain-Barré syndrome",
          "Guillain-Barré-Strohl syndrome",
          "post-infectious polyneuritis",
          "post-infective polyneuritis",
          "postinfectious polyneuritis",
          "Landry's ascending paralysis",
          "Landry-Guillain-Barre-Strohl syndrome",
          "acute autoimmune peripheral neuropathy",
          "acute immune-mediated polyneuropathy",
          "acute inflammatory demyelinating polyneuropathy",
          "acute inflammatory neuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A spectrum of rare post-infectious neuropathies that usually occur in otherwise healthy patients. GBS is clinically heterogeneous and encompasses acute inflammatory demyelinating polyradiculoneuropathy (AIDP), acute motor axonal neuropathy (AMAN) and acute motor-sensory axonal neuropathy (AMSAN), Miller-Fisher syndrome (MFS) and some other regional variants."
      },
      "child_count": 22,
      "reference_id": "MONDO:0016218"
    },
    {
      "id": 24270,
      "label": "hereditary neurological disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6799
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "neurogenetic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A heterogeneous group of genetic conditions with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology characterized by abnormalities in the brain, spinal cord, nerves, or muscles."
      },
      "child_count": 528,
      "reference_id": "MONDO:0100545"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16801,
      "label": "Guillain-Barre syndrome"
    },
    {
      "id": 24270,
      "label": "hereditary neurological disease"
    }
  ]
}