{
  "id": 9108,
  "label": "epidermolytic palmoplantar keratoderma, 1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007758",
  "properties": {
    "xrefs": [
      "DOID:0070552",
      "GARD:0002826",
      "ICD9:757.39",
      "NCIT:C84693",
      "OMIM:144200",
      "Orphanet:2199",
      "SCTID:399955009"
    ],
    "synonyms": [
      "EPPK",
      "diffuse erythrodermic palmoplantar keratoderma, VC6rner type",
      "diffuse erythrodermic palmoplantar keratoderma, Voerner type",
      "epidermolytic palmoplantar keratoderma of VC6rner",
      "epidermolytic palmoplantar keratoderma of Voerner",
      "Ppke",
      "diffuse erythrodermic palmoplantar keratoderma, Vörner type",
      "epidermolytic palmoplantar keratoderma of Vörner",
      "hyperkeratosis palmoplantar localised epidermolytic",
      "hyperkeratosis palmoplantar localized epidermolytic",
      "hyperkeratosis, localised epidermolytic",
      "hyperkeratosis, localized epidermolytic",
      "keratoderma, epidermolytic palmoplantar",
      "keratosis of Greither",
      "keratosis palmaris Et plantaris Familiaris",
      "palmoplantar keratoderma, Vorner type",
      "palmoplantar keratoderma, epidermolytic",
      "palmoplantar keratoderma, epidermolytic, with knuckle pads",
      "tylosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A genetic skin disorder caused by mutations in the KRT9 gene. It is characterized by hyperkeratosis in the palms and soles resulting in abnormal thickening of the skin in these areas."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 17917,
      "label": "diffuse palmoplantar keratoderma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19132
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021289",
          "HP:0007435",
          "ICD9:757.39",
          "MEDGEN:7201",
          "Orphanet:307141",
          "SCTID:400123002",
          "UMLS:C0022584",
          "icd11.foundation:1259583500"
        ],
        "synonyms": [
          "diffuse PPK",
          "diffuse keratosis palmoplantaris",
          "diffuse palmoplantar hyperkeratosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Palmoplantar keratoderma that diffusely involves most of the palm and sole and is caused by a genetic abnormality."
      },
      "child_count": 32,
      "reference_id": "MONDO:0017666"
    },
    {
      "id": 25959,
      "label": "palmoplantar keratoderma, epidermolytic",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19132
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080223",
          "GARD:0027034",
          "MEDGEN:354561",
          "OMIMPS:144200",
          "UMLS:C1721006"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0968949"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 17917,
      "label": "diffuse palmoplantar keratoderma"
    },
    {
      "id": 25959,
      "label": "palmoplantar keratoderma, epidermolytic"
    }
  ]
}