{
  "id": 9120,
  "label": "hyperpigmentation with or without hypopigmentation, familial progressive",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007771",
  "properties": {
    "xrefs": [
      "DOID:0111373",
      "GARD:0018073",
      "MEDGEN:333550",
      "OMIM:145250",
      "UMLS:C1840392"
    ],
    "synonyms": [
      "hyperpigmentation with or without hypopigmentation",
      "hyperpigmentation with or without hypopigmentation, familial progressive",
      "macules, hereditary congenital hypopigmented and hyperpigmented",
      "melanosis, universal",
      "FPHH",
      "hyperpigmentation, familial progressive, 2",
      "hyperpigmentation, familial progressive, 2, formerly",
      "melanosis universalis hereditaria"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 14672,
      "label": "familial progressive hyperpigmentation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19140
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016706",
          "OMIM:614233",
          "Orphanet:79146",
          "SCTID:715630006",
          "icd11.foundation:1808730427"
        ],
        "synonyms": [
          "melanosis diffusa congenita",
          "melanosis universalis hereditaria",
          "universal melanosis",
          "FPH1",
          "Fph",
          "hyperpigmentation, familial progressive, 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Familial progressive hyperpigmentation is a rare, genetic, skin pigmentation anomaly disorder characterized by irregular patches of hyperpigmented skin which present at birth or in early infancy and increase in size, number and confluence with age. Affected areas of the body include the face, neck, trunk and limbs, as well as the palms, soles, oral mucosa and conjuctiva. No hypogmentation macules are observed and no systemic diseases are associated."
      },
      "child_count": 1,
      "reference_id": "MONDO:0013648"
    },
    {
      "id": 23867,
      "label": "hereditary skin disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MESH:D012873",
          "SCTID:239001006"
        ],
        "synonyms": [
          "disease, genetic skin",
          "diseases, genetic skin",
          "genetic skin disease",
          "genetic skin diseases",
          "genodermatosis",
          "skin disease, genetic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of skin disease that is caused by a modification of the individual's genome."
      },
      "child_count": 228,
      "reference_id": "MONDO:0100118"
    }
  ],
  "children": [
    {
      "id": 17577,
      "label": "familial progressive hyper- and hypopigmentation",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9120
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017298",
          "MEDGEN:1643385",
          "Orphanet:280628",
          "UMLS:C4706423",
          "icd11.foundation:1229773662"
        ],
        "synonyms": [
          "FPHH"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Familial progressive hyper- and hypopigmentation is a rare, genetic, skin pigmentation anomaly disorder characterized by progressive, diffuse, partly blotchy, hyperpigmented lesions that are intermixed with multiple café-au-lait spots, hypopigmented maculae and lentigines and are located on the face, neck, trunk and limbs, as well as, frequently, the palms, soles and oral mucosa. Dispigmentation pattern can range from well isolated café-au-lait/hypopigmented patches on a background of normal-appearing skin to confetti-like or mottled appearance."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017239"
    }
  ],
  "roots": [
    {
      "id": 14672,
      "label": "familial progressive hyperpigmentation"
    },
    {
      "id": 23867,
      "label": "hereditary skin disorder"
    }
  ]
}