{
  "id": 9152,
  "label": "autosomal dominant ichthyosis vulgaris",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007810",
  "properties": {
    "xrefs": [
      "DOID:1702",
      "GARD:0027780",
      "ICD10CM:Q80.0",
      "MEDGEN:609440",
      "OMIM:146700",
      "Orphanet:462",
      "SCTID:254157005",
      "UMLS:C0432300"
    ],
    "synonyms": [
      "autosomal dominant ichthyosis vulgaris",
      "ichthyosis vulgaris, autosomal dominant",
      "dominant ichthyosis vulgaris",
      "ichthyosis simplex",
      "ichthyosis vulgaris"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "Ichthyosis vulgaris is a common skin disorder passed down through families that leads to dry, scaly skin. It often begins in early childhood. Treatment may include heavy duty moisturizers which contain chemicals that help the skin to shed normally, including lactic acid, salicylic acid, and urea. Ichthyosis vulgaris can be a nuisance, but it rarely affects overall health. The condition usually disappears during adulthood, but may return in later years. This condition is inherited in an autosomal dominant pattern."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 2903,
      "label": "autosomal dominant disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2905
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050736",
          "ICD9:758.5",
          "MEDGEN:539206",
          "SCTID:11164009",
          "UMLS:C0265385"
        ],
        "synonyms": [
          "autosomal dominant disease or disorder",
          "autosomal dominant hereditary disorder",
          "autosomal dominant inherited disorder",
          "disease or disorder, autosomal dominant",
          "disease, autosomal dominant"
        ],
        "definition": "Autosomal dominant form of disease."
      },
      "child_count": 192,
      "reference_id": "MONDO:0000426"
    },
    {
      "id": 21337,
      "label": "ichthyosis vulgaris",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16624
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0006752",
          "MEDGEN:38217",
          "MESH:D016112",
          "NCIT:C84778",
          "UMLS:C0079584",
          "icd11.foundation:841161884"
        ],
        "synonyms": [
          "ichthyosis vulgaris",
          "common ichthyosis",
          "fish scale disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "The most common form of ichthyosis. It is an autosomal dominant inherited or acquired disorder characterized by scaling and desquamation of the skin."
      },
      "child_count": 1,
      "reference_id": "MONDO:0024304"
    }
  ],
  "children": [
    {
      "id": 24200,
      "label": "mild ichthyosis vulgaris",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9152
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026235"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of ichthyosis vulgaris in which the disease presentation is mild in severity. Heterozygote FLG mutation carriers often have mild manifestations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100474"
    },
    {
      "id": 24201,
      "label": "severe ichthyosis vulgaris",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9152
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026236"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of ichthyosis vulgaris in which the disease presentation is severe in severity. Homozygous FLG mutation carriers often have more severe manifestations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100475"
    }
  ],
  "roots": [
    {
      "id": 2903,
      "label": "autosomal dominant disease"
    },
    {
      "id": 21337,
      "label": "ichthyosis vulgaris"
    }
  ]
}