{
  "id": 9208,
  "label": "LADD syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007872",
  "properties": {
    "xrefs": [
      "DOID:0050331",
      "DOID:0081370",
      "GARD:0006848",
      "ICD9:759.89",
      "MEDGEN:78545",
      "MESH:C538132",
      "NORD:1345",
      "OMIMPS:149730",
      "Orphanet:2363",
      "SCTID:23817003",
      "UMLS:C0265269"
    ],
    "synonyms": [
      "LACRIMOAURICULODENTODIGITAL syndrome",
      "LADD syndrome",
      "Lacrimo-auriculo-dento-digital syndrome",
      "Lacrimoauriculodento-digital syndrome",
      "Lacrimoauriculoradiodental syndrome",
      "Levy Hollister syndrome",
      "Levy-Hollister syndrome",
      "lacrimoauriculodentodigital syndrome",
      "lard syndrome",
      "LADD"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "A multiple congenital anomaly syndrome characterized by hypoplasia, aplasia or atresia of the lacrimal system; anomalies of the ears and hearing loss; hypoplasias, apalsias or atresias of the salivary glands; dental anomalies and digital malformations."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 2903,
      "label": "autosomal dominant disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2905
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050736",
          "ICD9:758.5",
          "MEDGEN:539206",
          "SCTID:11164009",
          "UMLS:C0265385"
        ],
        "synonyms": [
          "autosomal dominant disease or disorder",
          "autosomal dominant hereditary disorder",
          "autosomal dominant inherited disorder",
          "disease or disorder, autosomal dominant",
          "disease, autosomal dominant"
        ],
        "definition": "Autosomal dominant form of disease."
      },
      "child_count": 192,
      "reference_id": "MONDO:0000426"
    },
    {
      "id": 16089,
      "label": "multiple congenital anomalies/dysmorphic syndrome without intellectual disability",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18951
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019833",
          "MEDGEN:1842829",
          "Orphanet:102285",
          "UMLS:C5680373"
        ],
        "synonyms": [
          "MCA without intellectual disability",
          "multiple congenital anomalies without intellectual disability with or without dysmorphism"
        ]
      },
      "child_count": 168,
      "reference_id": "MONDO:0015161"
    },
    {
      "id": 24804,
      "label": "polydactyly-syndactyly-triphalangism",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18360,
        20258,
        20259
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026428"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Any skeletal dysplasia that is characterizedby polydactyly, syndactyly and triphalangism, where a digit has three phalanges instead of two."
      },
      "child_count": 84,
      "reference_id": "MONDO:0800066"
    }
  ],
  "children": [
    {
      "id": 24038,
      "label": "LADD syndrome 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026132",
          "MEDGEN:1824096",
          "OMIM:149730",
          "UMLS:C5774323"
        ],
        "synonyms": [
          "LADD1",
          "lacrimoauriculodentodigital syndrome 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Any LADD syndrome in which the cause of the disease is a variation in the FGFR2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100302"
    },
    {
      "id": 25545,
      "label": "lacrimoauriculodentodigital syndrome 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081371",
          "GARD:0026750",
          "MEDGEN:1824059",
          "OMIM:620192",
          "UMLS:C5774286"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0859577"
    },
    {
      "id": 25546,
      "label": "lacrimoauriculodentodigital syndrome 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081372",
          "GARD:0026751",
          "MEDGEN:1824060",
          "OMIM:620193",
          "UMLS:C5774287"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0859578"
    }
  ],
  "roots": [
    {
      "id": 2903,
      "label": "autosomal dominant disease"
    },
    {
      "id": 16089,
      "label": "multiple congenital anomalies/dysmorphic syndrome without intellectual disability"
    },
    {
      "id": 24804,
      "label": "polydactyly-syndactyly-triphalangism"
    }
  ]
}