{
  "id": 9221,
  "label": "Legg-Calve-Perthes disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007885",
  "properties": {
    "xrefs": [
      "DOID:14415",
      "GARD:0006874",
      "MEDGEN:730669",
      "MESH:D007873",
      "MedDRA:10034735",
      "NCIT:C34766",
      "NORD:1353",
      "OMIM:150600",
      "Orphanet:2380",
      "SCTID:15739006",
      "UMLS:C1442965"
    ],
    "synonyms": [
      "Legg Calvé Perthes Disease",
      "Legg-CALVE-Perthes disease",
      "Legg-Calve-Perthes disease",
      "Legg-Calve-Perthes symptom",
      "Legg-Calve-Perthes syndrome",
      "Legg-Calvé-Perthes disease",
      "Legg-Perthes disease",
      "Osteochondrosis of the capital femoral epiphysis",
      "Perthe's disease",
      "Perthes disease",
      "aseptic necrosis of the capital femoral epiphysis",
      "osteochondritis of the capital femoral epiphysis",
      "LCPD",
      "Lcp",
      "osteochondritis deformans"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A hip region disease that is characterized by uni- or bilateral avascular necrosis (AVN) of the femoral head in children. In a small percentage of cases, mutations in the COL2A1 gene were found to be responsible."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18460,
      "label": "osteochondrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7060
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8125",
          "GARD:0012704",
          "ICD10CM:M42",
          "ICD9:732.6",
          "MEDGEN:18216",
          "MESH:D055034",
          "NCIT:C34879",
          "Orphanet:399319",
          "SCTID:19579005",
          "UMLS:C0029429",
          "icd11.foundation:1446309782"
        ],
        "synonyms": [
          "osteochondrosis not specified as adult or juvenile, of unspecified site",
          "osteochondritis",
          "osteochondritis juvenilis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A condition that is characterized by defective bone growth that affects the growth centers of bone."
      },
      "child_count": 11,
      "reference_id": "MONDO:0018381"
    },
    {
      "id": 18462,
      "label": "osteonecrosis of genetic origin",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        7060
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021667",
          "MEDGEN:1842788",
          "Orphanet:399380",
          "UMLS:C5680035"
        ],
        "synonyms": [
          "bone necrosis of genetic origin",
          "genetic osteonecrosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "An instance of osteonecrosis that is caused by a modification of the individual's genome."
      },
      "child_count": 24,
      "reference_id": "MONDO:0018383"
    },
    {
      "id": 29221,
      "label": "dysplasia of the proximal femoral epiphyses",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20997
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027112",
          "MEDGEN:481394",
          "UMLS:C3279764"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A developmental disorder affecting the growth and development of the proximal end of the femur (thigh bone) near the hip joint characterized by avascular necrosis of the femoral head, cystic changes of the femoral head, and/or sclerosis of the femoral head. It is a relatively milder form of the other skeletal disorders associated with COL2A1."
      },
      "child_count": 3,
      "reference_id": "MONDO:1030002"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18460,
      "label": "osteochondrosis"
    },
    {
      "id": 18462,
      "label": "osteonecrosis of genetic origin"
    },
    {
      "id": 29221,
      "label": "dysplasia of the proximal femoral epiphyses"
    }
  ]
}