{
  "id": 9222,
  "label": "uterine corpus leiomyoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007886",
  "properties": {
    "xrefs": [
      "DOID:13223",
      "EFO:0000731",
      "GARD:0024585",
      "HP:0000131",
      "ICD10CM:D25",
      "ICD9:218",
      "ICD9:218.9",
      "MEDGEN:21801",
      "NCIT:C3434",
      "OMIM:150699",
      "ONCOTREE:ULM",
      "SCTID:95315005",
      "UMLS:C0042133"
    ],
    "synonyms": [
      "body of uterus fibroid",
      "body of uterus leiomyoma",
      "corpus uteri fibroid",
      "corpus uteri leiomyoma",
      "fibroid of body of uterus",
      "fibroid of corpus uteri",
      "fibroid of the body of uterus",
      "fibroid of the corpus uteri",
      "fibroid of the uterine body",
      "fibroid of the uterine corpus",
      "fibroid of uterine body",
      "fibroid of uterine corpus",
      "leiomyoma of body of uterus",
      "leiomyoma of corpus uteri",
      "leiomyoma of the body of uterus",
      "leiomyoma of the corpus uteri",
      "leiomyoma of the uterine body",
      "leiomyoma of the uterine corpus",
      "leiomyoma of uterine body",
      "leiomyoma of uterine corpus",
      "uterine body fibroid",
      "uterine body leiomyoma",
      "uterine corpus fibroid",
      "uterine corpus leiomyoma",
      "uterine corpus leiomyomata",
      "uterine fibroid",
      "UL",
      "leiomyoma, uterine",
      "uterine leiomyoma",
      "uterus fibroma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 11,
  "parents": [
    {
      "id": 3776,
      "label": "leiomyoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7677
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:127",
          "ICD9:215.9",
          "ICDO:8890/0",
          "MEDGEN:9710",
          "MESH:D007889",
          "NCIT:C3157",
          "SCTID:146801000119103",
          "UMLS:C0023267"
        ],
        "synonyms": [
          "fibroid",
          "fibroid neoplasm",
          "fibroid tumor",
          "fibroid tumour",
          "leiomyoma, benign",
          "leiomyomatous neoplasm (morphologic abnormality)",
          "leiomyomatous tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A well-circumscribed benign smooth muscle neoplasm characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern."
      },
      "child_count": 30,
      "reference_id": "MONDO:0001572"
    },
    {
      "id": 6889,
      "label": "fibroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050871",
          "EFO:0002424",
          "ICD9:215.9",
          "ICDO:8810/0",
          "MEDGEN:42016",
          "MESH:D005350",
          "NCIT:C3041",
          "SCTID:424568000",
          "UMLS:C0016045"
        ],
        "synonyms": [
          "fibroma",
          "fibroma, benign"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A non-metastasizing neoplasm arising from the fibrous tissue. It is characterized by the presence of spindle-shaped fibroblasts."
      },
      "child_count": 11,
      "reference_id": "MONDO:0005167"
    },
    {
      "id": 20643,
      "label": "benign neoplasm of corpus uteri",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3037,
        20461
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:219.1",
          "MEDGEN:57808",
          "NCIT:C3608",
          "SCTID:92021007",
          "UMLS:C0153998"
        ],
        "synonyms": [
          "benign corpus uteri neoplasm",
          "benign corpus uteri tumor",
          "benign corpus uteri tumour",
          "benign neoplasm of body of uterus",
          "benign neoplasm of the body of uterus",
          "benign neoplasm of the corpus uteri",
          "benign neoplasm of the uterine body",
          "benign neoplasm of the uterine corpus",
          "benign neoplasm of uterine body",
          "benign neoplasm of uterine corpus",
          "benign tumor of body of uterus",
          "benign tumor of corpus uteri",
          "benign tumor of the body of uterus",
          "benign tumor of the corpus uteri",
          "benign tumor of the uterine body",
          "benign tumor of the uterine corpus",
          "benign tumor of uterine body",
          "benign tumor of uterine corpus",
          "benign tumour of body of uterus",
          "benign tumour of corpus uteri",
          "benign tumour of the body of uterus",
          "benign tumour of the corpus uteri",
          "benign tumour of the uterine body",
          "benign tumour of the uterine corpus",
          "benign tumour of uterine body",
          "benign tumour of uterine corpus",
          "benign uterine body neoplasm",
          "benign uterine body tumor",
          "benign uterine body tumour",
          "benign uterine corpus neoplasm",
          "benign uterine corpus tumor",
          "benign uterine corpus tumour",
          "body of uterus benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign neoplasm that involves the body of uterus."
      },
      "child_count": 10,
      "reference_id": "MONDO:0021525"
    },
    {
      "id": 21247,
      "label": "hereditary disorder of connective tissue",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        5762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:473110",
          "NCIT:C97075",
          "SCTID:363045008",
          "UMLS:C0410787"
        ],
        "synonyms": [
          "Mendelian connective tissue disorder",
          "connective tissue hereditary disorder",
          "hereditary connective tissue disorder",
          "Hereditary Connective Tissue Disorder",
          "Inherited disorder of connective tissue",
          "inherited disorder of connective tissue"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "An inherited genetic disorder that affects the connective tissues. Representative examples include Ehlers-Danlos syndrome and Marfan syndrome."
      },
      "child_count": 176,
      "reference_id": "MONDO:0023603"
    }
  ],
  "children": [
    {
      "id": 3858,
      "label": "submucous uterine fibroid",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13222",
          "GARD:0022984",
          "ICD10CM:D25.0",
          "ICD9:218.0",
          "MEDGEN:509501",
          "SCTID:95279007",
          "UMLS:C0153993"
        ],
        "synonyms": [
          "submucous leiomyoma of uterus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001664"
    },
    {
      "id": 3931,
      "label": "subserous uterine fibroid",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13560",
          "GARD:0023001",
          "ICD9:218.2",
          "MEDGEN:509503",
          "SCTID:95280005",
          "UMLS:C0153995"
        ],
        "synonyms": [
          "subserous leiomyoma of uterus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001745"
    },
    {
      "id": 4019,
      "label": "uterine corpus epithelioid leiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13951",
          "GARD:0023018",
          "MEDGEN:275554",
          "NCIT:C40164",
          "UMLS:C1519850"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A morphologic variant of uterine corpus leiomyoma characterized by the presence of round or polygonal epithelioid smooth muscle cells forming clusters."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001841"
    },
    {
      "id": 4020,
      "label": "uterine corpus dissecting leiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13953",
          "GARD:0023019",
          "MEDGEN:275552",
          "NCIT:C40172",
          "UMLS:C1519847"
        ],
        "synonyms": [
          "Cotyledonoid dissecting leiomyoma",
          "Sternberg tumor",
          "Sternberg tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A rare morphologic variant of uterine corpus leiomyoma. Macroscopically, it is characterized by large, fungating, and multinodular neoplasm masses arising from the uterine corpus, and extending into the broad ligament or the peritoneal cavity. Microscopically, it shows neoplastic smooth muscle cells infiltrating the myometrium. The neoplastic cells are arranged in a micronodular pattern. Hydropic changes and increased vascularity are also present."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001842"
    },
    {
      "id": 4021,
      "label": "uterus interstitial leiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13955",
          "GARD:0023020",
          "ICD10CM:D25.1",
          "ICD9:218.1",
          "MEDGEN:509502",
          "SCTID:93616000",
          "UMLS:C0153994"
        ],
        "synonyms": [
          "intramural leiomyoma of uterus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0001843"
    },
    {
      "id": 4022,
      "label": "uterine corpus myxoid leiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13956",
          "GARD:0023021",
          "MEDGEN:275558",
          "NCIT:C40166",
          "UMLS:C1519860"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A morphologic variant of uterine corpus leiomyoma characterized by extensive myxoid degeneration of the neoplasm connective tissue stroma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001844"
    },
    {
      "id": 4023,
      "label": "uterine corpus lipoleiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13957",
          "GARD:0023022",
          "MEDGEN:311424",
          "NCIT:C40168",
          "UMLS:C1519856"
        ],
        "synonyms": [
          "uterine corpus lipomatous leiomyoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A rare morphologic variant of uterine corpus leiomyoma characterized by the presence of scattered islands of mature adipocytes within the smooth muscle neoplasm."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001845"
    },
    {
      "id": 4024,
      "label": "uterine corpus bizarre leiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5229,
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13958",
          "GARD:0023023",
          "MEDGEN:275555",
          "NCIT:C40167",
          "UMLS:C1519853"
        ],
        "synonyms": [
          "bizarre leiomyoma of body of uterus",
          "body of uterus bizarre leiomyoma",
          "uterine corpus Symplastic leiomyoma",
          "uterine corpus bizarre leiomyoma",
          "uterine corpus leiomyoma with bizarre nuclei",
          "uterine corpus leiomyoma, atypical variant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A morphologic variant of uterine corpus leiomyoma characterized by significant cytologic atypia. The atypical cells are large with pleomophic hyperchromatic nuclei."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001846"
    },
    {
      "id": 5586,
      "label": "uterine corpus diffuse leiomyomatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5236,
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5916",
          "DOID:5917",
          "GARD:0023624",
          "MEDGEN:275556",
          "NCIT:C40170",
          "UMLS:C1519855"
        ],
        "synonyms": [
          "body of uterus leiomyomatosis",
          "leiomyomatosis of body of uterus",
          "uterine corpus diffuse leiomyomatosis",
          "uterine corpus leiomyomatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "An unusual condition characterized by the presence of numerous small benign smooth muscle neoplasms located throughout the body of the uterus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003704"
    },
    {
      "id": 5986,
      "label": "uterine corpus apoplectic leiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7241",
          "GARD:0023855",
          "MEDGEN:274364",
          "NCIT:C40165",
          "UMLS:C1519852"
        ],
        "synonyms": [
          "uterine corpus hemorrhagic cellular leiomyoma",
          "uterine corpus leiomyoma with apoplectic change"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A morphologic variant of uterine corpus leiomyoma characterized by zones of hemorrhagic infarction surrounded by hypercellular areas. It usually develops in women of childbearing years, particularly those that are pregnant, post-partum, or taking oral contraceptives."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004161"
    },
    {
      "id": 5987,
      "label": "uterine corpus cellular leiomyoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5237,
        9222
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7242",
          "GARD:0023856",
          "MEDGEN:276938",
          "NCIT:C40163",
          "UMLS:C1519845"
        ],
        "synonyms": [
          "body of uterus cellular leiomyoma",
          "cellular leiomyoma of body of uterus",
          "uterine corpus cellular leiomyoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A morphologic variant of leiomyoma arising from the uterine corpus. It is characterized by a dense cellular infiltrate composed of spindle or round cells with scant cytoplasm and a less obvious interlacing fascicle pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004162"
    }
  ],
  "roots": [
    {
      "id": 3776,
      "label": "leiomyoma"
    },
    {
      "id": 6889,
      "label": "fibroma"
    },
    {
      "id": 20643,
      "label": "benign neoplasm of corpus uteri"
    },
    {
      "id": 21247,
      "label": "hereditary disorder of connective tissue"
    }
  ]
}