{
  "id": 9297,
  "label": "Melkersson-Rosenthal syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0007969",
  "properties": {
    "xrefs": [
      "DOID:1761",
      "EFO:1001039",
      "GARD:0007010",
      "ICD10CM:G51.2",
      "MEDGEN:6291",
      "MESH:D008556",
      "MedDRA:10027166",
      "NCIT:C84886",
      "NORD:1429",
      "OMIM:155900",
      "Orphanet:2483",
      "UMLS:C0025235"
    ],
    "synonyms": [
      "Melkersson's syndrome",
      "Melkersson-Rosenthal syndrome",
      "MRS",
      "Melkersson syndrome",
      "Mros",
      "cheilitis Granulomatosa"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      }
    ],
    "definition": "The Melkersson-Rosenthal syndrome is a rare disorder characterized by a triad of recurrent orofacial swelling, relapsing facial paralysis and fissured tongue and onset in childhood or early adolescence. It has an estimated incidence of 8/10,000. The etiology is unknown but hereditary predisposition is suspected."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4235,
      "label": "facial nerve disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5469,
        5512
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1756",
          "EFO:1002051",
          "ICD10CM:G51",
          "ICD9:351",
          "ICD9:351.9",
          "MEDGEN:41946",
          "MESH:D005155",
          "NCIT:C27594",
          "SCTID:422426003",
          "UMLS:C0015464"
        ],
        "synonyms": [
          "disease of facial nerve",
          "disease or disorder of facial nerve",
          "disorder of facial nerve",
          "facial nerve disease",
          "facial nerve disease or disorder",
          "facial nerve disorder",
          "disorder of seventh cranial nerve",
          "disorders of the VIIth cranial nerve",
          "disorders of the seventh nerve",
          "facial neuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disease involving the facial nerve."
      },
      "child_count": 18,
      "reference_id": "MONDO:0002098"
    },
    {
      "id": 4239,
      "label": "cheilitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6519,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1762",
          "HP:0100825",
          "MEDGEN:3349",
          "MESH:D002613",
          "NCIT:C79545",
          "SCTID:7847004",
          "UMLS:C0007971",
          "icd11.foundation:482914030"
        ],
        "synonyms": [
          "inflammation of lip",
          "lip inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "An inflammatory process affecting the lip."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002102"
    },
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 7148,
      "label": "urticaria",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4496
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1555",
          "EFO:0005531",
          "HP:0001025",
          "ICD10CM:L50",
          "ICD10WHO:L50",
          "ICD9:708",
          "ICD9:708.8",
          "ICD9:708.9",
          "MEDGEN:22587",
          "MESH:D014581",
          "NCIT:C3432",
          "SCTID:126485001",
          "UMLS:C0042109"
        ],
        "synonyms": [
          "hives",
          "urticaria",
          "urticaria (disease)",
          "Urticarias"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress."
      },
      "child_count": 14,
      "reference_id": "MONDO:0005492"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4235,
      "label": "facial nerve disorder"
    },
    {
      "id": 4239,
      "label": "cheilitis"
    },
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 7148,
      "label": "urticaria"
    }
  ]
}