{
  "id": 9427,
  "label": "ocular cicatricial pemphigoid",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0008109",
  "properties": {
    "xrefs": [
      "EFO:0008610",
      "GARD:0008759",
      "MEDGEN:266181",
      "MedDRA:10067776",
      "NCIT:C84939",
      "OMIM:164185",
      "Orphanet:99922",
      "SCTID:314757003",
      "SCTID:34250006",
      "UMLS:C1282359",
      "icd11.foundation:953963439"
    ],
    "synonyms": [
      "ocular cicatricial pemphigoid",
      "ocular pemphigoid",
      "OCP",
      "cicatricial pemphigoid, ocular",
      "pemphigoid, ocular cicatricial"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Ocular cicatricial pemphigoid (OCP) is a form of mucous membrane pemphigoid (a group of rare, chronic autoimmune disorders) that affects the eyes. In the early stages, people with OCPgenerally experience chronic or relapsing conjunctivitis that is often characterized by tearing, irritation, burning, and/or mucus drainage. If left untreated, OCP can progress to severe conjunctiva scarring and vision loss. Involvement of other mucosal sites and the skin may also occur in OCP. The exact underlying cause is currently unknown. The treatment of OCP aims to slow disease progression and prevent complications. This usually involves long-term use of medications called immunomodulators which help regulate or normalize the immune system."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18714,
      "label": "mucous membrane pemphigoid",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19177
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11656",
          "EFO:1000680",
          "GARD:0005913",
          "ICD10CM:L12.1",
          "ICD9:694.6",
          "ICD9:694.61",
          "MEDGEN:10619",
          "MedDRA:10057052",
          "NANDO:1200634",
          "NCIT:C34907",
          "Orphanet:46486",
          "SCTID:34250006",
          "SCTID:76092003",
          "UMLS:C0030804",
          "icd11.foundation:1456138933"
        ],
        "synonyms": [
          "Mucosynechial pemphigoid",
          "benign mucous Membrane pemphigoid",
          "cicatricial pemphigoid",
          "mucosal pemphigoid",
          "benign mucosal pemphigoid",
          "benign mucous membrane pemphigoid",
          "benign mucous membrane pemphigoid with ocular involvement",
          "cicatricial pemphigoid with ocular involvement",
          "ocular pemphigoid",
          "ocular pemphigus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Mucous membrane pemphigoid is a bullous dermatosis characterized clinically by blistering of the mucous membranes followed by scarring, and immunologically by IgG, IgA and/or C3 deposits on the epidermal basement membrane."
      },
      "child_count": 1,
      "reference_id": "MONDO:0018746"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18714,
      "label": "mucous membrane pemphigoid"
    }
  ]
}