{
  "id": 9496,
  "label": "hereditary chronic pancreatitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0008185",
  "properties": {
    "xrefs": [
      "GARD:0006632",
      "ICD9:577.8",
      "MEDGEN:116056",
      "MESH:C537262",
      "NANDO:1200921",
      "NANDO:2200942",
      "NCIT:C95436",
      "OMIM:167800",
      "Orphanet:676",
      "SCTID:68072000",
      "UMLS:C0238339",
      "icd11.foundation:1287702961"
    ],
    "synonyms": [
      "hereditary chronic pancreatitis",
      "hereditary pancreatitis",
      "HPC",
      "Hp",
      "PCTT",
      "autosomal dominant hereditary pancreatitis",
      "familial pancreatitis",
      "pancreatitis, calcific",
      "pancreatitis, calcific, included",
      "pancreatitis, chronic",
      "pancreatitis, chronic pancreatitis, chronic, susceptibility to, included",
      "pancreatitis, chronic, protection against",
      "pancreatitis, chronic, protection against, included",
      "pancreatitis, chronic, susceptibility to",
      "pancreatitis, hereditary"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Hereditary chronic pancreatitis (HCP), a rare inherited form of pancreatitis is defined as recurrent acute pancreatitis and/or chronic pancreatitis in two first-degree relatives or 3 or more second-degree relatives in 2 or more generations, for which no predisposing factors are identified. HCP is characterized by irreversible damage to both exocrine and endocrine components of the pancreas."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    },
    {
      "id": 6741,
      "label": "chronic pancreatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6723
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0051065",
          "EFO:0000342",
          "ICD9:577.1",
          "MEDGEN:101753",
          "MESH:D050500",
          "NCIT:C84637",
          "SCTID:235494005",
          "UMLS:C0149521",
          "icd11.foundation:1758007371"
        ],
        "synonyms": [
          "pancreatitis, chronic"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A chronic inflammatory process causing damage and fibrosis of the pancreatic parenchyma. Signs and symptoms include abdominal pain, malabsorption and diabetes mellitus."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005003"
    }
  ],
  "children": [
    {
      "id": 13057,
      "label": "tropical pancreatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9496
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016946",
          "MEDGEN:334069",
          "MESH:C564276",
          "OMIM:608189",
          "Orphanet:103918",
          "SCTID:724540009",
          "UMLS:C1842402",
          "icd11.foundation:1645607956"
        ],
        "synonyms": [
          "TCP",
          "tropical calcific chronic pancreatitis",
          "fibrocalculous pancreatic diabetes, susceptibility to",
          "tropical calcific pancreatitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Tropical pancreatitis is a rare pancreatic disease of juvenile onset occurring mainly in tropical developing countries and characterized by chronic non-alcoholic pancreatitis manifesting with abdominal pain, steatorrhea and fibrocalculous pancreatopathy. It is also commonly associated with the development of pancreatic calculi and pancreatic cancer at a much higher frequency than seen in ordinary chronic pancreatitis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011986"
    },
    {
      "id": 26304,
      "label": "autosomal recessive hereditary chronic pancreatitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9496
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:700124"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0979356"
    }
  ],
  "roots": [
    {
      "id": 5714,
      "label": "hereditary disease"
    },
    {
      "id": 6741,
      "label": "chronic pancreatitis"
    }
  ]
}