{
  "id": 9847,
  "label": "thrombophilia due to activated protein C resistance",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0008560",
  "properties": {
    "xrefs": [
      "DOID:0111902",
      "GARD:0024631",
      "ICD9:289.81",
      "MEDGEN:396074",
      "MESH:D020016",
      "OMIM:188055",
      "SCTID:421527008",
      "UMLS:C1861171"
    ],
    "synonyms": [
      "thrombophilia 2 due to activated protein C resistance",
      "thrombophilia due to activated protein C resistance",
      "APC resistance",
      "Activated Protein C resistance",
      "Pccf deficiency",
      "Proc cofactor deficiency",
      "THPH2",
      "resistance, APC",
      "thrombophilia 5",
      "thrombophilia due to ACTIVATED PROTEIN C resistance",
      "thrombophilia due to Factor 5 Leiden",
      "thrombophilia due to deficiency of Activated Protein C cofactor",
      "thrombophilia, susceptibility to, due to factor V Leiden"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4359,
      "label": "coagulation protein disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2212",
          "GARD:0023096",
          "MEDGEN:108723",
          "MESH:D020147",
          "NCIT:C27215",
          "SCTID:86075001",
          "UMLS:C0600503"
        ],
        "synonyms": [
          "coagulation factor deficiency",
          "coagulation factor deficiency syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Congenital or acquired deficiency of one of the coagulation factors. It results in bleeding."
      },
      "child_count": 28,
      "reference_id": "MONDO:0002242"
    },
    {
      "id": 23980,
      "label": "inherited thrombophilia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4413,
        20411
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026094",
          "MEDGEN:391721",
          "OMIMPS:188050",
          "UMLS:C2584620"
        ],
        "synonyms": [
          "hereditary hypercoagulable disorder",
          "hereditary thrombophilia",
          "thrombophilia, hereditary"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An instance of thrombophilia that is inherited."
      },
      "child_count": 24,
      "reference_id": "MONDO:0100240"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4359,
      "label": "coagulation protein disease"
    },
    {
      "id": 23980,
      "label": "inherited thrombophilia"
    }
  ]
}