{
  "id": 9856,
  "label": "thyroid hormone resistance, generalized, autosomal dominant",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0008569",
  "properties": {
    "xrefs": [
      "GARD:0024633",
      "MEDGEN:424846",
      "MESH:C567934",
      "OMIM:188570",
      "UMLS:C2937288"
    ],
    "synonyms": [
      "thyroid hormone resistance",
      "thyroid hormone resistance, generalized, autosomal dominant",
      "GRTH",
      "Gthr",
      "hyperthyroxinemia, familial euthyroid, secondary to pituitary and peripheral resistance to thyroid hormones",
      "thyroid hormone unresponsiveness"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 10294,
      "label": "generalized resistance to thyroid hormone",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3557,
        6233
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000301",
          "MEDGEN:1654700",
          "Orphanet:3221",
          "UMLS:C4722330"
        ],
        "synonyms": [
          "GRTH",
          "Refetoff syndrome",
          "deafness-thyroid hormone resistance syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A thyroid hormone resistance syndrome characterized by resistance in the pituitary gland and in most or all of the peripheral tissues."
      },
      "child_count": 12,
      "reference_id": "MONDO:0009043"
    },
    {
      "id": 24776,
      "label": "resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3557
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0028049",
          "Orphanet:566243"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare genetic hyperthyroidism characterized by elevated levels of circulating free thyroid hormones, normal or elevated thyroid-stimulating hormone, decreased peripheral tissue responses to iodothyronine action, and a highly variable clinical phenotype which most commonly includes goiter, resting tachycardia, osteoporosis, short stature, and attention deficit disorder. Some patients may be entirely asymptomatic."
      },
      "child_count": 3,
      "reference_id": "MONDO:0700478"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 10294,
      "label": "generalized resistance to thyroid hormone"
    },
    {
      "id": 24776,
      "label": "resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta"
    }
  ]
}