{
  "id": 9939,
  "label": "vitiligo",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0008661",
  "properties": {
    "xrefs": [
      "DOID:12306",
      "EFO:0004208",
      "ICD10CM:L80",
      "ICD10WHO:L80",
      "ICD9:709.01",
      "MEDGEN:22677",
      "MESH:D014820",
      "NCIT:C26915",
      "Orphanet:247871",
      "UMLS:C0042900",
      "icd11.foundation:1894744640"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4496,
      "label": "dermatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6820,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2723",
          "ICD9:692.9",
          "MEDGEN:849741",
          "MESH:D003872",
          "NCIT:C2983",
          "SCTID:43116000",
          "UMLS:C3875321"
        ],
        "synonyms": [
          "inflammation of skin",
          "inflammation of the skin",
          "inflammation of zone of skin",
          "inflammatory skin disease",
          "skin inflammation",
          "zone of skin inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An inflammatory process affecting the skin. Signs include red rash, itching, and blister formation. Representative examples are contact dermatitis, atopic dermatitis, and seborrheic dermatitis."
      },
      "child_count": 66,
      "reference_id": "MONDO:0002406"
    },
    {
      "id": 8586,
      "label": "autoimmune disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6778
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:417",
          "EFO:0005809",
          "ICD9:279.4",
          "ICD9:279.49",
          "ICD9:720",
          "MEDGEN:2135",
          "MESH:D001327",
          "NCIT:C2889",
          "OBI:1110054",
          "OMIM:109100",
          "SCTID:85828009",
          "UMLS:C0004364"
        ],
        "synonyms": [
          "autoimmune disease",
          "autoimmune disease or disorder",
          "autoimmune disorder",
          "disease, autoimmune",
          "autoimmune hypersensitivity disease",
          "hypersensitivity reaction type II disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to their own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis)."
      },
      "child_count": 47,
      "reference_id": "MONDO:0007179"
    }
  ],
  "children": [
    {
      "id": 20767,
      "label": "alopecia universalis onychodystrophy vitiligo",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6660,
        9939
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000615",
          "MEDGEN:444049",
          "MESH:C537056",
          "UMLS:C2931408"
        ],
        "synonyms": [
          "alopecia universalis, onychodystrophy, and total vitiligo"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A syndrome characterized by total alopecia (hair loss), total vitíligo, and nail changes. The nail changes consist of fine pitting, associated with softness, and friability and may include horizontal splitting. The vitiligo is characterized by complete, rapid uniform loss of pigment which occurs without going through a patchy state. The entire cutaneous surface is light and translucent-appearing and is prone to burning on exposure to the sun."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021851"
    },
    {
      "id": 26544,
      "label": "trichrome vitiligo",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9939
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:697977",
          "SCTID:403270009",
          "UMLS:C1274649"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Any form of vitiligo characterized by a tan zone of varying width between normal and depigmented skin. This intermediate tan zone has more inflammatory cells, Langerhans cells, and melanophages than vitiliginous or normal skin. The number of melanocytes is greater than in vitiliginous skin but fewer than in normal skin."
      },
      "child_count": 0,
      "reference_id": "MONDO:1010122"
    },
    {
      "id": 26547,
      "label": "generalized vitiligo",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        9939
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:725821",
          "UMLS:C1304470"
        ],
        "synonyms": [
          "generalised vitiligo",
          "mixed vitiligo"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "Any form of vitiligo characterized by loss of pigment (depigmentation) in patches of skin all over the body."
      },
      "child_count": 0,
      "reference_id": "MONDO:1010125"
    }
  ],
  "roots": [
    {
      "id": 4496,
      "label": "dermatitis"
    },
    {
      "id": 8586,
      "label": "autoimmune disease"
    }
  ]
}